1507365-99-2

Basic information

• Product Name: C₁₂H₉F₃OS₂
• Synonyms: C₁₂H₉F₃OS₂
• CAS NO: 1507365-99-2
• Molecular Weight: 290.33
• Mol File: 1507365-99-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₉F₃OS₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₉F₃OS₂(1507365-99-2)
• EPA Substance Registry System: C₁₂H₉F₃OS₂(1507365-99-2)

Safety Data

• Hazardous Substances Data: 1507365-99-2(Hazardous Substances Data)

Upstream product

• 1610889-30-9 2-deutero-2-(1,3-dithiolan-2-ylidene)-1-phenylethanone 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 5653-30-5 2-[1,3]dithiolan-2-ylidene-1-phenyl-ethanone 
• 98-86-2 acetophenone 
• 17537-31-4 Acetophenone-methyl-d3 

Relevant articles and documents

Copper-catalyzed trifluoromethylation of internal olefinic C-H bonds: Efficient routes to trifluoromethylated tetrasubstituted olefins and N-heterocycles

The functionalization of internal olefins has been a challenging task in organic synthesis. Efficient CuII-catalyzed trifluoromethylation of internal olefins, that is, α-oxoketene dithioacetals, has been achieved by using Cu(OH)2 as a catalyst and TMSCF3 as a trifluoromethylating reagent. The push-pull effect from the polarized olefin substrates facilitates the internal olefinic C-H trifluoromethylation. Cyclic and acyclic dithioalkyl α-oxoketene acetals were used as the substrates and various substituents were tolerated. The internal olefinic C-H bond cleavage was not involved in the rate-determining step, and a mechanism that involves radicals is proposed based on a TEMPO-quenching experiment of the trifluoromethylation reaction. Further derivatization of the resultant CF 3 olefins led to multifunctionalized tetrasubstituted CF3 olefins and trifluoromethylated N-heterocycles.