150767-06-9 Usage
Description
2-(t-Butyloxycarbonyl)amino-4S-hydroxy-5S-(benzyloxycarbonyl)amino-1,6-diphenyl-2-azahexane, also known as Boc-Asn(Trt)-Ser-OH, is a complex chemical compound that is widely used in the fields of organic chemistry and biochemistry. It is a peptide derivative with protective groups that are essential in solid-phase peptide synthesis, ensuring that the peptide chain remains unaltered during the synthesis process. 2-(t-Butyloxycarbonyl)amino-4S-hydroxy-5S-(benzyloxycarbonyl)amino-1,6 -diphenyl-2-azahexane is specifically designed to protect the Asparagine and Serine amino acids, enabling selective deprotection and subsequent coupling reactions. The presence of Boc and Trt protective groups in the compound allows for easy removal under mild conditions, making it a valuable tool in the synthesis of complex peptides and proteins. Overall, 2-(t-Butyloxycarbonyl)amino-4S-hydroxy-5S-(benzyloxycarbonyl)amino-1,6-diphenyl-2-azahexane plays a crucial role in the production and study of peptides and proteins in various research and pharmaceutical applications.
Uses
Used in Organic Chemistry:
2-(t-Butyloxycarbonyl)amino-4S-hydroxy-5S-(benzyloxycarbonyl)amino-1,6-diphenyl-2-azahexane is used as a protective agent for [Asparagine and Serine amino acids] in [solid-phase peptide synthesis], allowing for [selective deprotection and subsequent coupling reactions].
Used in Biochemistry:
2-(t-Butyloxycarbonyl)amino-4S-hydroxy-5S-(benzyloxycarbonyl)amino-1,6-diphenyl-2-azahexane is used as a peptide derivative in [the synthesis of complex peptides and proteins], providing [protection and easy removal of protective groups under mild conditions].
Used in Pharmaceutical Applications:
2-(t-Butyloxycarbonyl)amino-4S-hydroxy-5S-(benzyloxycarbonyl)amino-1,6-diphenyl-2-azahexane is used as a key component in [the production and study of peptides and proteins], contributing to [various research and pharmaceutical applications].
Check Digit Verification of cas no
The CAS Registry Mumber 150767-06-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,7,6 and 7 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 150767-06:
(8*1)+(7*5)+(6*0)+(5*7)+(4*6)+(3*7)+(2*0)+(1*6)=129
129 % 10 = 9
So 150767-06-9 is a valid CAS Registry Number.
InChI:InChI=1/C30H37N3O5/c1-30(2,3)38-29(36)32-33(20-24-15-9-5-10-16-24)21-27(34)26(19-23-13-7-4-8-14-23)31-28(35)37-22-25-17-11-6-12-18-25/h4-18,26-27,34H,19-22H2,1-3H3,(H,31,35)(H,32,36)/t26-,27-/m0/s1
150767-06-9Relevant articles and documents
Antiretroviral hydrazine derivatives
-
, (2008/06/13)
The invention relates to compounds of formula STR1 and salts, pharmaceutical compositions, intermediates and processes of preparation thereof.
Facile Synthesis of Potent HIV-1 Protease Inhibitors containing a Novel Pseudo-symmetric Dipeptide Isostere
Sham, Hing L.,Betebenner, David A.,Zhao, Chen,Wideburg, Norman E.,Saldivar, Ayda,et al.
, p. 1052 - 1053 (2007/10/02)
A series of potent inhibitors of the HIV-1 protease containing a novel pseudo-symmetric dipeptide isostere 3 was synthesized via ring opening of a protected epoxide with various substituted hydrazines.
