150805-64-4

Basic information

• Product Name: (4-Cyano-phenyl)-phosphonic acid diethyl ester
• Synonyms: (4-CYANO-PHENYL)-PHOSPHONIC ACID DIETHYL ESTER;Benzenepropanal, 4-acetyl-;3-(4-acetylphenyl)propanal
• CAS NO: 150805-64-4
• Molecular Formula: C₁₁H₁₂O₂
• Molecular Weight: 239.21
• Mol File: 150805-64-4.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 299.859°C at 760 mmHg
• Flash Point: 111.977°C
• Appearance: /
• Density: 1.051g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.516
• CAS DataBase Reference: (4-Cyano-phenyl)-phosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Cyano-phenyl)-phosphonic acid diethyl ester(150805-64-4)
• EPA Substance Registry System: (4-Cyano-phenyl)-phosphonic acid diethyl ester(150805-64-4)

Safety Data

• Hazardous Substances Data: 150805-64-4(Hazardous Substances Data)

Usage

General Description

The chemical compound (4-Cyano-phenyl)-phosphonic acid diethyl ester is a phosphonic acid ester with a cyano-phenyl group attached. It is commonly used as a reagent in organic synthesis and as a building block for the preparation of various organic compounds. It has a wide range of applications in the pharmaceutical, agricultural, and polymer industries, where it is used as a stabilizer, flame retardant, and as a component in the production of plasticizers and adhesives. (4-Cyano-phenyl)-phosphonic acid diethyl ester is considered to be stable under normal conditions, but caution should be taken when handling it, as it may pose potential health hazards and environmental risks.

InChI:InChI=1/C11H12O2/c1-9(13)11-6-4-10(5-7-11)3-2-8-12/h4-8H,2-3H2,1H3

Upstream product

• 10537-63-0 1-(4-vinylphenyl)ethanone 
• 201230-82-2 carbon monoxide 
• 13329-40-3 4-Iodoacetophenone 
• 107-18-6 allyl alcohol 
• 149104-90-5 4-acetylphenylboronic acid 
• 99-90-1 para-bromoacetophenone 
• 127921-76-0 (E)-3-(4-acetylphenyl)acrylaldehyde 
• 35573-93-4 3-chloro-1,1-diethoxy-propane 

Downstream Products

• 127921-76-0 (E)-3-(4-acetylphenyl)acrylaldehyde 
• 1334709-37-3 3-(4-acetylphenyl)-1-(4-methoxyphenyl)propan-1-one 
• 862893-82-1 3-(4-acetylphenyl)-2-propenal 

Relevant articles and documents

Me2s-induced highly selective reduction of aldehydes in the presence of ketones involving aldehyde-selective rate enhancement: A triruthenium cluster-catalyzed hydrosilylation

Addition of appropriate amounts of Me2S unusually accelerated the hydrosilylation of aldehydes catalyzed by [Ru3(CO)7(Acy)] (1, Acy: μ3-η2,η3,η5-acenaphthylene). The reduction of

Enantioselective Iridium-Catalyzed Allylation of Acetylenic Ketones via 2-Propanol-Mediated Reductive Coupling of Allyl Acetate: C14-C23 of Pladienolide D

Highly enantioselective catalytic reductive coupling of allyl acetate with acetylenic ketones occurs in a chemoselective manner in the presence of aliphatic or aromatic ketones. This method was used to construct C14-C23 of pladienolide D in half the steps previously required.

Replacing a stoichiometric silver oxidant with air: Ligated Pd(II)-catalysis to β-aryl carbonyl derivatives with improved chemoselectivity

Air was employed as a green reoxidant of Pd(0), replacing stoichiometric and toxic silver salt, in the chelation-controlled Pd(II)-modulated arylative enolization of prop-2-en-1-ols to acquire synthetically-important β-aryl carbonyl derivatives. This green approach, which didn't require acid or base, allowed the compatibility of a range of functionalities (inclusive of -I, -Br & -Cl), resulting in the construction of structurally-diverse dihydrochalcones, α-benzyl-α′-alkyl acetones, α-benzyl β-keto esters and dihydrocinnamaldehydes. In addition to organoboronic acids, efficient coupling was also achieved with boronic esters and trifluoroborate salts. A deuterium labelling experiment revealed an interesting 1,2-hydrogen shift after β-arylation in the catalytic process. the Partner Organisations 2014.