150928-21-5

Basic information

• Product Name: 3-[({3-(chlorocarbonyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]phenyl}carbonyl)amino]propane-1,2-diyl diacetate
• Synonyms: rac-3-(2,3-Diacetoxypropylcarbamoyl)-2,4,6-triiodo-5-methoxyacetylaminobenzoyl chloride;Benzoyl chloride, 3-[[[2,3-bis(acetyloxy)propyl]amino]carbonyl]-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-
• CAS NO: 150928-21-5
• Molecular Formula: C₁₈H₁₈ClI₃N₂O₈
• Molecular Weight: 806.5105
• EINECS: 604-759-4
• Mol File: 150928-21-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 689.6°C at 760 mmHg
• Flash Point: 370.9°C
• Density: 2.096g/cm³
• Vapor Pressure: 7.2E-19mmHg at 25°C
• Refractive Index: 1.652
• PKA: 10.44±0.70(Predicted)
• CAS DataBase Reference: 3-[({3-(chlorocarbonyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]phenyl}carbonyl)amino]propane-1,2-diyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[({3-(chlorocarbonyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]phenyl}carbonyl)amino]propane-1,2-diyl diacetate(150928-21-5)
• EPA Substance Registry System: 3-[({3-(chlorocarbonyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]phenyl}carbonyl)amino]propane-1,2-diyl diacetate(150928-21-5)

Safety Data

• Hazardous Substances Data: 150928-21-5(Hazardous Substances Data)

Upstream product

• 76350-04-4 5-methoxyacetylamino-2,4,6-triiodoisophthalic acid (2,3-dihydroxypropyl)amide chloride 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 

Downstream Products

• 1193076-40-2 5-methoxyacetylamino-2,4,6-triiodoisophthalic acid [(2,3-dihydroxy-N-methylpropyl)-(2,3-diacetoxypropyl)]diamide 

Relevant articles and documents

NOVEL PROCESS FOR PREPARATION OF IOPROMIDE

The present invention relates to a novel process for preparing iopromide which is used as a contrast agent for X-ray, wherein 5-methoxyacetylamino-2,4,6-triiodoisophthalic acid (2,3-diacetoxypropyl)amide chloride of formula (19) and 5-methoxyacetylamino-2,4,6-triiodoisophthalic acid [(2,3-dihydroxy-N-methylpropyl)-(2,3-diacetoxypropyl)]diamide of formula (20) are introduced as intermediates, by which a bismer by-product generated during the preparation process can be removed even without an additional removal procedure and thus iopromide with high purity can be prepared in high yield.