15095-70-2Relevant academic research and scientific papers
Dihydropyrancarboxamides related to zanamivir: A new series of inhibitors of influenza virus sialidases. 1. Discovery, synthesis, biological activity, and structure-activity relationships of 4-guanidino- and 4-amino-4h-pyran-6-carboxamides
Smith, Paul W.,Sollis, Steven L.,Howes, Peter D.,Cherry, Peter C.,Starkey, Lan D.,Cobley, Kevin N.,Weston, Helen,Scicinski, Jan,Merritt, Andrew,Whittington, Andrew,Wyatt, Paul,Taylor, Neil,Green, Darren,Bethell, Richard,Madar, Safia,Fenton, Robert J.,Morley, Peter J.,Pateman, Tony,Beresford, Alan
, p. 787 - 797 (2007/10/03)
4-Amino- and 4-guanidino-4ff-pyran-6-carboxamides 4 and 5 related to zanamivir (GG167) are a new class of inhibitors of influenza virus sialidases. Structure-activity studies reveal that, in general, secondary amides are weak inhibitors of both influenza
