150994-93-7Relevant academic research and scientific papers
Phenytoin-lipid conjugates as potential prodrugs of phenytoin
Scriba
, p. 477 - 481 (1993)
Phenytoin-1-triglycerides and phenytoin-2-triglycerides were synthesized as potential prodrugs of phenytoin by covalent binding of 3-hydroxymethylphenytoin by succinic acid to the positions 1 and 2 of diglycerides, respectively. The corresponding 1- and 2
METHOD OF PREPARING DENDRITIC DRUGS
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Page/Page column 29, (2010/11/28)
Synthetic design of drug-incorporated novel dendrimer structures for quantitatively controlled drug delivery. The dendritic drugs have better control and thus a quantitative drug release can be obtained. There are no prior art dendritic drugs that control release both sequentially and quantitatively like the dendritic drugs disclosed herein. The dendritic drugs are formed by incorporating multiple same type drug units or more than two different drug types into a dendritic cascade structure to form a dendrimer drug.
Synthesis of salicylate dendritic prodrugs
Tang, Shengzhuang,June, Stephen M.,Howell, Bob A.,Chai, Minghui
, p. 7671 - 7675 (2007/10/03)
A small drug molecule, salicylic acid, has been converted into well-defined dendritic macromolecules. The mono-disperse nature of these materials may be clearly shown by NMR and GPC. A third generation salicylic acid dendrimer contains sixty salicylic aci
