151003-65-5

Basic information

• Product Name: syn-(4S,2'S,3'R)-3-(2'-azido-3'-hydroxy-3'-phenyl-propionyl)-4-(1-methylethyl)-2-oxazolidinone
• Synonyms: syn-(4S,2'S,3'R)-3-(2'-azido-3'-hydroxy-3'-phenyl-propionyl)-4-(1-methylethyl)-2-oxazolidinone
• CAS NO: 151003-65-5
• Molecular Weight: 318.332
• Mol File: 151003-65-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: syn-(4S,2'S,3'R)-3-(2'-azido-3'-hydroxy-3'-phenyl-propionyl)-4-(1-methylethyl)-2-oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: syn-(4S,2'S,3'R)-3-(2'-azido-3'-hydroxy-3'-phenyl-propionyl)-4-(1-methylethyl)-2-oxazolidinone(151003-65-5)
• EPA Substance Registry System: syn-(4S,2'S,3'R)-3-(2'-azido-3'-hydroxy-3'-phenyl-propionyl)-4-(1-methylethyl)-2-oxazolidinone(151003-65-5)

Safety Data

• Hazardous Substances Data: 151003-65-5(Hazardous Substances Data)

Upstream product

• 112459-60-6 (4S)-4-isopropyl-3-[(2E)-3-phenylprop-2-enoyl]-1,3-oxazolidin-2-one 
• 127181-72-0 anti-(4S,2'S,3'S)-3-(3'-Hydroxy-3'-phenyl-2'-bromo-1'-oxopropyl)-4-(1-methylethyl)-2-oxazolidinone 
• 127181-71-9 anti-(4S,2'R,3'R)-3-(3'-Hydroxy-3'-phenyl-2'-bromo-1'-oxopropyl)-4-(1-methylethyl)-2-oxazolidinone 
• 100-52-7 benzaldehyde 
• 93617-86-8 (4S)-(+)-3-bromoacetyl-4-(1-methylethyl)-2-oxazolidinone 

Downstream Products

• 46032-98-8 (1R,2R)-2-amino-1-phenylpropane-1,3-diol 
• 912296-87-8 syn-(2R,3R)-[2-azido-3-hydroxy-3-phenyl-1-propanol] 

Relevant articles and documents

Stereoselective syntheses of (-)-chloramphenicol and (+)-thiamphenicol

Chloramphenicol and thiamphenicol have been enantioselectively synthesized using an asymmetric halohydrin reaction as a key step. In particular, halomethoxylation reaction was used, where O-methyl functions as a hydroxyl protecting group and eliminates an additional protection step.