151061-72-2Relevant academic research and scientific papers
Synthesis of new analogues of salacinol containing a pendant hydroxymethyl group as potential glycosidase inhibitors
Nasi, Ravindranath,Pinto, B. Mario
, p. 2305 - 2311 (2007/10/03)
The synthesis of new analogues of the naturally occurring glycosidase inhibitor, salacinol, and its ammonium analogue, ghavamiol is described. These analogues contain an additional hydroxymethyl group at C-1, which was intended to form additional polar co
Studies on the formation of a tricyclic C2-symmetric sulfide
Winn, Caroline L.,Goodman, Jonathan M.
, p. 7091 - 7093 (2007/10/03)
Attempts to synthesise chiral sulfide 1 from the dimesylate precursor 5, via a cyclisation reaction using sodium sulfide in dimethyl sulfoxide, led to the unexpected formation of an unsymmetrical furan derivative 8. Studies were made into the effect of changing the leaving group, and changing the solvent of reaction. The desired compound could be synthesized in good yields from the xanthate 9 using a radical-mediated procedure.
