15109-98-5Relevant academic research and scientific papers
A Ba/Pd Catalytic System Enables Dehydrative Cross-Coupling and Excellent E-Selective Wittig Reactions
Xie, Peizhong,Fu, Weishan,Cai, Xinying,Sun, Zuolian,Wu, Ying,Li, Shuangshuang,Gao, Cuiqing,Yang, Xiaobo,Loh, Teck-Peng
supporting information, p. 7055 - 7059 (2019/09/12)
A Ba/Pd cooperative catalysis system was developed to enable the dehydrative cross-coupling of allylic alcohols with P-ylides to occur directly and promote a subsequent Wittig reaction in one pot. A variety of multisubstituted 1,4-dienes were isolated in good to excellent yields with broad P-ylides (stabilized by both ester and ketone carbonyl groups) and aldehyde (aliphatic and aromatic) substrates with excellent E selectivity.
Potassium 2-oxo-3-enoates as Effective and Versatile Surrogates for α, β-Unsaturated Aldehydes in NHC-Catalyzed Asymmetric Reactions
Gao, Yaru,Ma, Yafei,Xu, Chen,Li, Lin,Yang, Tianjian,Sima, Guoqing,Fu, Zhenqian,Huang, Wei
supporting information, p. 479 - 484 (2017/12/26)
Potassium 2-oxo-3-enoates, which are readily prepared at scale and easily stored, have been found to be effective and versatile surrogates for α,β-unsaturated aldehydes in NHC-catalyzed asymmetric reactions. Promoted by chiral N-heterocyclic carbenes combined with LiCl, these easy-to-handle solid salts could release of CO2 and then undergo asymmetric reactions via homoenolate and α, β-unsaturated acyl azolium intermediate. The reactions have broad substrate scopes with high enantioselectivities. (Figure presented.).
Synthesis of trifluoromethyl-/cyclopropyl-substituted 2-isoxazolines by DBU-promoted domino reaction
Liu, Xiao-Dong,Ma, Hai-Yan,Xing, Chun-Hui,Lu, Long
supporting information, p. 1780 - 1783 (2017/07/27)
NTrifluoromethyl and cyclopropyl substituted 2-isoxazolines were synthesized via a DBU-promoted domino reaction of β-trifluoromethyl-/β-cyclopropyl-substituted enones with hydroxylamine. The domino reaction consists of a Michael addition and the followed cyclization. A wide range of 3-substituted 5-cyclopropyl-5- trifluoromethyl-2-isoxazolines were obtained in good to excellent yields under mild reaction conditions. The method could also apply to other trifluoromethyl-substituted enones.
Iodine-mediated intramolecular amination of ketones: The synthesis of 2-acylindoles and 2-acylindolines by tuning N-protecting groups
Gao, Wen-Chao,Jiang, Shan,Wang, Ruo-Lin,Zhang, Chi
, p. 4890 - 4892 (2013/07/05)
A general method for constructing both 2-acylindoles and 2-acylindolines via I2-mediated intramolecular C-N bond formation is presented, and the selective formation of either 2-acylindoles or 2-acylindolines just depends on the nitrogen protecting groups used in the same substrate skeletons. The Royal Society of Chemistry.
Edge-Shared [M2Cl10]2- complexes of reaction between oxophilic group 4 metal and phosphorus ylides1
Sabounchei,Ahmadi,Shahriari,Hoseini-Fashami,Samiee
experimental part, p. 1005 - 1013 (2012/10/08)
The reactions between oxophilic group 4 metal chlorides, α-keto ylides in THF, led to the forma-tion of titanium, zirconium and hafnium edge-shared [M2Cl10]2- complexes (1a-3f). We describe that the reaction between MClsu
New access to trisubstitutea 3-pyrrolines under phosphine catalysis
Schuler, Marie,Duvvuru, Deepti,Retailleau, Pascal,Betzer, Jean-Francois,Marinetti, Angela
supporting information; scheme or table, p. 4406 - 4409 (2009/12/26)
Conjugated dienes, properly activated by electron-withdrawing groups on both ends, are shown to be suitable substrates for phosphinepromoted organocatalytic processes. Their reactions with imines, under phosphine catalysis, afford a new and efficient synthetic approach to functionalized 3-pyrrolines.
Synthesis and characterization of transition metal (Hg(II), Ag(I) and Cd(II)) complexes of some new: Phosphorus ylides
Sabounchei, S. Javad,Jodaian, Vida,Nemattalab, Hassan
experimental part, p. 9 - 13 (2010/08/19)
Reaction of two new phosphorus ylides Ph3PCHCOC 10H7 (Y1) and Ph3PCHCOC 4H3S(Y2) with mercury(II) halides and a previously reported ylide (P-tolyl)3PCHCOOCH
Synthesis and NMR study of α-keto stabilized ylides of the type RCOCH=PAr3, (R=MeO-C6H4, Cl-C6H 4, NO2-C6H4, α-thiophenyl and naphthyl; Ar = p-tolyl or phenyl)
Sabounchei, Seyyed Javad,Nemattalab, Hassan,Jodaian, Vida
scheme or table, p. 197 - 200 (2009/04/06)
Synthesis and characterization of five new phosphonium salts and related phosphorus ylides of the type R-COCH=PAr3 are reported. The reaction of bromo 4′-methoxo/chloro/nitro acetophenone, α-thiophenyl and naphthoyl acetophenone with triphenylp
