151098-20-3

Basic information

• Product Name: 3-(ethoxycarbonyl)-5-(4'-fluorophenyl)-1,2,4-oxadiazole
• Synonyms: 3-(ethoxycarbonyl)-5-(4'-fluorophenyl)-1,2,4-oxadiazole;Ethyl 5-(4-fluorophenyl)-1,2,4-oxadiazol-3-carboxylate;ethyl 5-(4-fluorophenyl)-1,2,4-oxadiazole-3-carboxylate
• CAS NO: 151098-20-3
• Molecular Formula: C₁₁H₉FN₂O₃
• Molecular Weight: 236.2
• Mol File: 151098-20-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(ethoxycarbonyl)-5-(4'-fluorophenyl)-1,2,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(ethoxycarbonyl)-5-(4'-fluorophenyl)-1,2,4-oxadiazole(151098-20-3)
• EPA Substance Registry System: 3-(ethoxycarbonyl)-5-(4'-fluorophenyl)-1,2,4-oxadiazole(151098-20-3)

Safety Data

• Hazardous Substances Data: 151098-20-3(Hazardous Substances Data)

Upstream product

• 403-43-0 4-fluorobenzoyl chloride 
• 151097-51-7 C₁₁H₁₁FN₂O₄ 

Downstream Products

• 1370025-77-6 5-(4'-fluorophenyl)-1,2,4-oxadiazole-3-carboxamide 
• 1370025-82-3 5-(4'-(morpholin-N-yl)phenyl)-1,2,4-oxadiazole-3-carboxamide 

Relevant articles and documents

Synthesis and preliminary antibacterial evaluation of Linezolid-like 1,2,4-oxadiazole derivatives

In the present study the synthesis of new Linezolid-like molecules has been achieved by substitution of the oxazolidinone central heterocyclic moiety with a 1,2,4-oxadiazole ring. Two series of 1,2,4-oxadiazoles, bearing different side-chains and containing a varying number of fluorine atoms, were synthesized and preliminarily tested for biological activity against some Gram-positive and Gram-negative bacteria using Linezolid and Ceftriaxone as reference drugs.