15110-95-9

Upstream product

• 100-52-7 benzaldehyde 
• 615-36-1 2-bromoaniline 
• 577-19-5 2-nitrophenyl bromide 
• 100-51-6 benzyl alcohol 

Downstream Products

• 71687-81-5 N-benzyl-2-bromoaniline 
• 758640-21-0 N-Benzylaniline 
• 1048636-57-2 cis-1-(2-bromophenyl)-2,3-diphenylaziridine 
• 945033-63-6 8-bromo-4-(triisopropylsilyl)methyl-2-phenylquinoline 
• 1075193-06-4 N-benzyl-2-bromo-N-methylaniline 
• 1449678-29-8 1-(2-bromophenyl)-3,3-dimethyl-4-phenylazetidin-2-one 
• 5438-81-3 3,3-dimethyl-1,4-diphenyl-azetidin-2-one 
• 1449678-31-2 C₁₈H₁₉NO 
• 1449678-32-3 C₂₄H₂₃NO₂ 
• 142505-64-4 2-amino-2'-isopropoxybiphenyl 

Relevant academic research and scientific papers

Efficient Grignard-type addition of sugar alkynes via C-H activation to imines using Cu-Ru catalyst under microwave conditions

Very productive Grignard-type addition of sugar alkynes to imines via C-H activation using Cu-Ru catalyst was achieved under microwave conditions. The resulting glyco-conjugates are attractive for future evaluation as potential drug-like molecules.

Accelerated generation of (protonated) imines and quinoxalines by formation of C=N bonds in the microdroplets of a nebuliser

Ions corresponding to protonated imines appear in the positive ion electrospray mass spectra of mixtures of the parent aromatic aldehyde and arylamine. The formation of these imine products occurs readily in the electrospray source nebuliser, even without

Iron-Catalyzed Hydrogen Transfer Reduction of Nitroarenes with Alcohols: Synthesis of Imines and Aza Heterocycles

A straightforward and selective reduction of nitroarenes with various alcohols was efficiently developed using an iron catalyst via a hydrogen transfer methodology. This protocol led specifically to imines in 30-91% yields, with a good functional group tolerance. Noticeably, starting from o-nitroaniline derivatives, in the presence of alcohols, benzimidazoles can be obtained in 64-72% yields when the reaction was performed with an additional oxidant, DDQ, and quinoxalines were prepared from 1,2-diols in 28-96% yields. This methodology, unprecedented at iron for imines, also provides a sustainable alternative for the preparation of quinoxalines and benzimidazoles.

Preparation method of fluorine-containing benzidine

The invention relates to the field of organic synthesis, in particular to a preparation method of fluorine-containing benzidine. The invention provides the preparation method of the fluorine-containing benzidine. The preparation method comprises the follo

Zeolite-catalyzed method for the preparation of 2,3-dihydroquinazolin-4(1H) -ones

The reaction of isatoic anhydride, amines, and aldehydes in the presence of a microporous zeolite gave 2,3-dihydroquinazolin-4(1H)-one derivatives with good to excellent yield. The yield depends on the structure of the aldehyde and/or amine compound. Copyright

General and selective reductive amination of carbonyl compounds using a core-shell structured Co3O4/NGr@C catalyst

The application of heterogenized non-noble metal-based catalysts in selective catalytic hydrogenation processes is still challenging. In this respect, the preparation of a well-defined cobalt-based catalyst was investigated by immobilization of the corresponding cobalt(ii)-phenanthroline-chelate on Vulcan XC72R carbon powder. The formed core-shell structured cobalt/cobalt oxide nanocomposites are encapsulated by nitrogen-enriched graphene layers. This promising cheap heterogeneous catalyst allows for an efficient domino reductive amination of carbonyl compounds with nitroarenes. This journal is

Halogen-metal exchange reactions of bromoaryl-substituted β-lactams

β-Lactams are quite susceptible to ring opening when exposed to nucleophilic reagents. The robustness of a variety of bromo- and iodoarenes containing electrophilic functional groups toward alkyllithium reagents during the halogen-lithium exchange process

Diastereoselective synthesis of tetrahydroquinolines via a palladium-catalyzed Heck-Suzuki cascade reaction

A method for the diastereoselective synthesis of tetrahydroquinolines via a palladium-catalyzed Suzuki terminated Heck reaction is described. The reaction provides access to tetrahydroquinolines containing both quaternary and tertiary stereocenters. Ligand effects, a rationale for the high level of diastereoselectivity, and a mechanistic hypothesis are discussed.

Potassium tert-butoxide promoted intramolecular arylation via a radical pathway

Potassium tert-butoxide mediated intramolecular cyclization of aryl ethers, amines, and amides was efficiently performed under microwave irradiation to provide the corresponding products in high regioisomeric ratios. The reaction proceeds via single-electron transfer to initiate the formation of an aryl radical, followed by a kinetically favored 5-exo-trig and subsequent ring expansion.

Preparation of secondary and tertiary amines from nitroarenes and alcohols

Various secondary amines were obtained selectively from the reaction of nitroarenes with primary alcohols in the presence of ruthenium(ii) complexes having phosphine-amine ligands as the catalyst. Secondary amines could be further alkylated with a primary alcohol using the same catalyst, but different conditions.