151213-43-3 Usage
Description
(4aR,7aR)-Octahydro-6-(phenylmethyl)-1H-Pyrrolo[3,4-b]pyridine is an organic compound with a unique molecular structure, characterized by its octahydro and phenylmethyl groups. It is a key intermediate in the synthesis of various pharmaceutical compounds due to its versatile chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
(4aR,7aR)-Octahydro-6-(phenylmethyl)-1H-Pyrrolo[3,4-b]pyridine is used as an intermediate in the synthesis of moxifloxacin (M745000), a fluorinated quinolone antibacterial. Its role in the synthesis process is crucial for the development of this potent antibiotic, which is effective against a wide range of bacterial infections.
Application Reason:
The compound's unique structure allows it to participate in various chemical reactions, making it a valuable building block for the creation of complex pharmaceutical compounds. Its use in the synthesis of moxifloxacin highlights its importance in the development of new and effective treatments for bacterial infections, contributing to the ongoing fight against antibiotic resistance.
Check Digit Verification of cas no
The CAS Registry Mumber 151213-43-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,2,1 and 3 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 151213-43:
(8*1)+(7*5)+(6*1)+(5*2)+(4*1)+(3*3)+(2*4)+(1*3)=83
83 % 10 = 3
So 151213-43-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H20N2/c1-2-5-12(6-3-1)9-16-10-13-7-4-8-15-14(13)11-16/h1-3,5-6,13-15H,4,7-11H2/t13-,14+/m1/s1
151213-43-3Relevant articles and documents
Racemisation of (1R, 6S)-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonane using halogenated solvent in basic medium
Bhavsar, Jigar,Bhashkar, Bhuwan,Kumar, Anil
, p. 241 - 246 (2013/06/27)
A simple, highly rapid, efficient and eco friendly process for Racemisation of (1R, 6S)-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0] nonane in various halogenated solvents has been carried out as a base catalysed reaction to afford racemic mixture in excellent yields (80-95%) at temperature of or below 40°C. The base catalysed racemisation in halogenated solvent has an advantage of simple workup procedure, and use of less volume of halogenated solvent irrespective of type of solvent used in the reaction system.
Quinolonecarboxylic acids
-
, (2008/06/13)
The invention relates to novel derivatives of quinolonecarboxylic acid and naphthyridonecarboxylic acid which are linked to a β-lactam antibiotic, to their salts, to processes for their preparation and to antibacterial agents containing these derivatives.