151222-57-0Relevant articles and documents
Palladium-Catalyzed Regiospecific peri- And ortho-C-H Oxygenations of Polyaromatic Rings Mediated by Tunable Directing Groups
Hu, Lihong,Jiang, Jing,Lin, Yaoyu,Ma, Congzhe,Song, Wanbin,Yuan, Dandan,Zhang, Yinan
supporting information, p. 279 - 284 (2021/01/13)
An efficient divergent approach of Pd-catalyzed C-H oxygenation of polyaromatic rings is described. Reversible directing groups enable regiospecific peri- and ortho-oxygenation to readily access a wide array of polyaromatic phenols without pre- and postmanipulation of directing groups. The systematic mechanistic investigation, including deuterium-labeling experiments, palladacycle trapping, and DFT calculations, reveals that the tunable ligand-assisted C-H bond cleavage played a crucial role during the reaction process.
Haloarenes in the Duff reaction under high pressures 2. Formylation and amidomethylation of haloarenes in trifluoroacetic acid
Sedishev, I. P.,Agafonov, N. E.,Kutin, A. A.,Zhulin, V. M.
, p. 2127 - 2130 (2007/10/03)
Reactions of haloarenes with urotropine in CF3COOH at elevated temperatures and high pressures give the corresponding aromatic aldehydes and/or N-(haloarylmethyl)trifluoroacetamides.The yields of the products and their ratio depend on electronic properties of substituents in the aromatic ring.The reaction carried out in a mixture of CF3COOH and (CF3CO)2O affords only amides. - Keywords: haloarenes; Duff reaction; high pressure; haloarenecarbaldehydes; N-(haloarylmethyl)trifluoroacetamides.
