16650-52-5

Usage

Uses

Used in Pharmaceutical Industry:
5-Chloro-1-naphthoic acid is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows for the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 5-chloro-1-naphthoic acid serves as an essential component in the production of certain pesticides and herbicides, contributing to effective crop protection.
Used in Dye and Pigment Industry:
5-Chloro-1-naphthoic acid is utilized in the synthesis of dyes and pigments, providing a range of colors for various applications, including textiles, plastics, and printing inks.
Used in Fluorescent Dye Production:
5-CHLORO-1-NAPHTHOIC ACID is used as a precursor in the manufacturing of fluorescent dyes, which are important for applications in bioimaging, diagnostics, and other specialized fields.
Used in Chemical Compound Manufacturing:
5-Chloro-1-naphthoic acid also acts as an intermediate in the production of other chemical compounds, expanding its utility across different industries that rely on organic synthesis.

InChI:InChI=1/C11H7ClO2/c12-10-6-2-3-7-8(10)4-1-5-9(7)11(13)14/h1-6H,(H,13,14)

Upstream product

• 86-55-5 1-naphthalenecarboxylic acid 
• 32018-88-5 5-amino-1-naphthoic acid 
• 73399-85-6 5-chloronaphthalene-1-carbonitrile 
• 216060-40-1 1-(5-amino-[1]naphthyl)-ethanone 
• 72016-73-0 5-Aminonaphthalene-1-carbonitrile 
• 7553-56-2 iodine 
• 7782-50-5 chlorine 
• 64-19-7 acetic acid 
• 444913-41-1 5-chloro-[1]naphthoic acid ethyl ester 
• 86-53-3 1-Cyanonaphthalene 
• 4053-08-1 p-chloro-1,8-naphthalicanhydride 
• 4766-33-0 5-amino-1-bromonaphthalene 
• 5328-76-7 1-bromo-5-nitronaphthalene 
• 86-57-7 1-Nitronaphthalene 

Downstream Products

• 151222-57-0 5-chloro-1-naphthoaldehyde 
• 73399-85-6 5-chloronaphthalene-1-carbonitrile 

Relevant academic research and scientific papers

The mercury-mediated decarboxylation (Pesci reaction) of naphthoic anhydrides investigated by microwave synthesis

The mercury-mediated decarboxylation (Pesci reaction) of several substituted naphthoic anhydrides has been investigated by microwave synthesis. A laboratory microwave reactor was found to be ideal for small-scale preparations of this slow reaction, reducing reaction times from typically four days to less than 1 h for the three-step process. The ionic reaction medium rapidly heated to high temperatures under microwave heating and could be efficiently maintained by low microwave power settings. Generation of stoichiometric CO2 was safely contained within the reaction tubes. A simplified reaction procedure has been developed. For substituted naphthoic anhydrides, 1H NMR analysis of the naphthoate ester derivatives indicated no change in the regioisomer ratio compared to previously reported thermal values.

AMINOETHANOL DERIVATIVES

The present invention provides a pharmaceutical agent having cholesteryl ester transfer protein inhibitory action and useful as a blood lipid lowering agent and the like. The present invention relates to a compound represented by the formula wherein Ar1 is an aromatic ring group optionally having substituents, Ar2 is an aromatic ring group having substituents, OR'' is an optionally protected hydroxyl group, R is an acyl group, R' is a hydrogen atom or a hydrocarbon group optionally having substituents, or a salt thereof, and a pharmaceutical composition containing a compound of the formula (I) or a salt thereof or a prodrug thereof.