1512860-68-2Relevant academic research and scientific papers
Synthesis of cycloalkyl substituted purine nucleosides: Via a metal-free radical route
Wang, Dong-Chao,Xia, Ran,Xie, Ming-Sheng,Qu, Gui-Rong,Guo, Hai-Ming
, p. 4189 - 4193 (2016/05/24)
An efficient route to synthesize cycloalkyl substituted purine nucleosides was developed. This metal-free C-H activation was accomplished by a tBuOOtBu initiated radical reaction. By adjusting the amount of tBuOOtBu and reaction time, the selective synthe
Radical route for the Alkylation of Purine Nucleosides at C6 via Minisci reaction
Xia, Ran,Xie, Ming-Sheng,Niu, Hong-Ying,Qu, Gui-Rong,Guo, Hai-Ming
supporting information, p. 444 - 447 (2014/04/03)
A highly regioselective Minisci reaction with the decarboxylative alkylation of purine nucleosides under mild conditions was developed. With 5 mol % AgNO3 as a catalyst and (NH4)2S 2O8 as an oxidant, a series of purine nucleosides including ribosyl, deoxyribosyl, arabinosyl purine nucleosides worked well with primary, secondary, and tertiary aliphatic carboxylic acids.
