15138-39-3Relevant academic research and scientific papers
The synthesis of trianglimines: On the scope and limitations of the [3 + 3] cyclocondensation reaction between (1R,2R)-diaminocyclohexane and aromatic dicarboxaldehydes
Kuhnert, Nikolai,Rossignolo, Giulia M.,Lopez-Periago, Ana
, p. 1157 - 1170 (2003)
The synthesis of aromatic dicarboxaldehydes, using dilithiation methodology is described along with their reactivity, in the [3 + 3] cyclocondensation reaction, with (1R,2R)-diaminocyclohexane to give trianglimine macrocycles. The scope and limitations of the cyclocondensation reaction are studied and some comments on the properties of the novel macrocycles are made such as their conformation in solution and temperature dependent dynamic NMR behaviour.
Aryllithiums with increasing steric crowding and lipophilicity prepared from chlorides in diethyl ether. the first directly prepared room-temperature-stable dilithioarenes
Screttas, Constantinos G.,Steele, Barry R.,Micha-Screttas, Maria,Heropoulos, Georgios A.
supporting information, p. 5680 - 5683 (2013/01/15)
A convenient procedure has been developed for the preparation of synthetically useful, room-temperature-stable aryllithiums starting from aryl chlorides and lithium metal. The method provides a route to aryllithiums which have previously not been accessible cleanly or could only be prepared by using more expensive starting materials.
Efficient photocyclization of o-alkylbenzaldehydes in the solid state: Direct observation of E-xylylenols en route to benzocyclobutenols
Moorthy,Mal,Natarajan,Venugopalan
, p. 7013 - 7019 (2007/10/03)
The photocyclization to benzocyclobutenols of o-alkyl aromatic aldehydes that are predestined for γ-hydrogen abstraction is found to occur efficiently in the solid state; in contrast, solution-phase photolysis is known to afford a mixture of several produ
Formylation and dichloromethylation as alternative directions of rieche reaction. A novel to the synthesis of sterically hindered aromatic dialdhydes
Yakubov, Alexander P.,Tsyganov, Dmitry V.,Belen'kii, Leonid I.,Krayushkin, Mikhail M.
, p. 3397 - 3404 (2007/10/02)
A previously unknown direction of Rieche reaction has been found: formylation of mesitylene, m-xylene, and durene with dichloromethyl methyl ether in the presence of aluminium trichloride and, to lesser extent, of titanium tetrachloride give the respective benzylidene dichlorides besides aldehydes. A novel approach to the synthesis of sterically hindered aromatic dialdehydes has been offered which involves the transformation of a monoaldehyde into the corresponding benzylidene dichloride, Rieche formylation of the latter, and hydrolysis of dichloromethyl aldehyde formed.
SYNTHESIS OF STERICALLY HINDERED AROMATIC ALDEHYDES
Yakubov, A. P.,Tsyganov, D. V.,Belen'kii, L. I.,Krayushkin, M. M.
, p. 1427 - 1432 (2007/10/02)
Formylation of mesitylene, durene, and m-xylene derivatives containing electron-donor and electron-acceptor substituents by dichloromethyl methyl ether was studied in the presence of TiCl4.A series of functionally substituted sterically hindered benzaldehydes was prepared from the products of these reactions.
NEW DATA ON THE FORMYLATION OF MESITYLENE AND DIMESITYLMETHANE BY DICHLOROMETHYL ETHER
Yakubov, A. P.,Tsyganov, D. V.,Belen'kii, L. I.,Krayushkin, M. M.
, p. 1707 - 1712 (2007/10/02)
During the formylation of mesitylene by the action of dichloromethyl methyl ether in the presence of aluminium chloride or titanium tetrachloride an appreciable amount of 2,4,6-trimethylbenzylidene chloride is formed.This indicates the possible appearance of the CHCl2+ cation as intermediate particle.The disubstituted products are formed in addition to the monosubstitution products.In addition to the corresponding dialdehyde, the formylation of dimesitylmethane leads to the formation of products which contain one benzene ring and appear during cleavage of thesubstrate and subsequent substitution (formylmesitylene, dichloromethylmesitylene, chloromethylmesitylenecarbaldehyde, chloromethyl-2,4,6-trimethylbenzylidene chloride).
