57386-83-1

Basic information

• Product Name: 1,3-DICHLORO MESITYLENE
• Synonyms: 2,4-DICHLORO MESITYLENE;1,3-DICHLORO MESITYLENE;1,3,5-Trimethyl-2,4-dichlorobenzene
• CAS NO: 57386-83-1
• Molecular Formula: C₉H₁₀Cl₂
• Molecular Weight: 189.08
• Mol File: 57386-83-1.mol
• Article Data: 8

Chemical Properties

• Melting Point: 59°C
• Boiling Point: 250.74°C (estimate)
• Appearance: /
• Density: 1.2476 (estimate)
• Refractive Index: 1.5590 (estimate)
• CAS DataBase Reference: 1,3-DICHLORO MESITYLENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-DICHLORO MESITYLENE(57386-83-1)
• EPA Substance Registry System: 1,3-DICHLORO MESITYLENE(57386-83-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 57386-83-1(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Solubility

Insoluble in water

Odor

Strong, aromatic

Uses

a. Solvent in industrial processes
b. Liquid crystalline polymers
c. Reaction medium in organic synthesis
d. Intermediate in production of dyes, pharmaceuticals, and agrochemicals

Toxicity

Low acute toxicity

Health hazards

a. Skin irritation
b. Eye irritation
c. Respiratory tract irritation

Safety precautions

Handle and store with caution to minimize risks to human health and the environment

Upstream product

• 7782-50-5 chlorine 
• 108-67-8 1,3,5-trimethyl-benzene 
• 1667-04-5 2-bromomesitylene 

Downstream Products

• 30075-62-8 3,5-Dichloro-2,4,6-trimethylbenzylchlorid 
• 487-68-3 mesytaldehyde 
• 15138-39-3 2,4,6-trimethylisophthalic dialdehyde 
• 1368226-27-0 ethyl (3-chloro-2,4,6-trimethylphenyl)-2-oxoacetate 
• 1407160-10-4 C₁₇H₂₀O₆ 
• 5524-57-2 ethyl 2-(2,4,6-trimethylphenyl)-2-oxoacetate 
• 856189-62-3 2,4-dichloro-1,3,5-tris-trichloromethyl-benzene 
• 384-86-1 2,4-dichloro-1,3,5-tris-trifluoromethyl-benzene 

Relevant articles and documents

Chlorination Reaction of Aromatic Compounds and Unsaturated Carbon-Carbon Bonds with Chlorine on Demand

Chlorination with chlorine is straightforward, highly reactive, and versatile, but it has significant limitations. In this Letter, we introduce a protocol that could combine the efficiency of electrochemical transformation and the high reactivity of chlorine. By utilizing Cl3CCN as the chloride source, donating up to all three chloride atom, the reaction could generate and consume the chlorine in situ on demand to achieve the chlorination of aromatic compounds and electrodeficient alkenes.

Metal and H2O2 free aerobic oxidative aromatic halogenation with [RNH3+] [NO3-]/HX and [BMIM(SO3H)][NO3)x(X)y] (X = Br, Cl) as multifunctional ionic liquids

Novel multifunctional ionic liquids (ILs) are generated by addition of HBr or HCl to alkylammonium nitrates ([RNH3+] [NO 3-]) and to 3-methyl-1-(butyl-4-sulfonyl)imidazolium nitrate ([BMIM(SO3H)][NO3]). The resulting [RNH 3+] [NO3-]/HX and mono (3-methyl-1-(butyl-4-sulfonyl)imidazolium) monohalogenide mononitrate ([BMIM(SO3H)][NO3)x(X)y] (X = Br, Cl)) systems act as solvent and promoter for aerobic oxidative halogenation of arenes under mild conditions in high yields that can be repeated over several cycles.

Chlorination of aromatics with trichloroisocyanuric acid (TCICA) in bronsted-acidic imidazolium ionic liquid [BMIM(SO3H)][OTf]: An economical, green protocol for the synthesis of chloroarenes

A survey study on electrophilic chlorination of aromatics with trichloroisocyanuric acid (TCICA) in Bronsted-acidic imidazolium ionic liquid [BMIM(SO3H)][OTf] is reported. The reactions are performed under very mild conditions (at ～50°C) and give good to excellent yields, depending on the substrates. Chemoselectivity for mono- v. dichlorination can be tuned by changing the arene-to-TCICA ratio and the reaction time. The survey study and competitive experiments suggest that triprotonated/protosolvated TCICA is a selective/moderately reactive transfer-chlorination electrophile. Density functional theory was used as guide to obtain further insight into the nature of the chlorination electrophile and the transfer-chlorination step. CSIRO 2007.