151389-59-2

Basic information

• Product Name: N1-(2-BROMOETHYL)-4-CHLOROBENZENE-1-SULFONAMIDE, TECH
• Synonyms: N1-(2-BROMOETHYL)-4-CHLOROBENZENE-1-SULFONAMIDE, TECH;N-(2-bromoethyl)-4-chlorobenzenesulfonamide
• CAS NO: 151389-59-2
• Molecular Formula: C₈H₉BrClNO₂S
• Molecular Weight: 298.58456
• Mol File: 151389-59-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N1-(2-BROMOETHYL)-4-CHLOROBENZENE-1-SULFONAMIDE, TECH(CAS DataBase Reference)
• NIST Chemistry Reference: N1-(2-BROMOETHYL)-4-CHLOROBENZENE-1-SULFONAMIDE, TECH(151389-59-2)
• EPA Substance Registry System: N1-(2-BROMOETHYL)-4-CHLOROBENZENE-1-SULFONAMIDE, TECH(151389-59-2)

Safety Data

• Hazardous Substances Data: 151389-59-2(Hazardous Substances Data)

Upstream product

• 107-09-5 2-bromoethylamine 
• 98-60-2 4-chlorobenzenesulfonyl chloride 
• 2576-47-8 2-bromoethylamine hydrobromide 

Downstream Products

• 50707-38-5 N-(4-chlorophenylsulphonyl)aziridine 
• 645393-52-8 C₁₄H₁₇BrClNO₆S 
• 6318-34-9 N-ethyl-4-chlorobenzenesulfonamide 
• 645393-28-8 6-chloro-3,4-dihydro-2H-benzo[e][1,2]thiazine 1,1-dioxide 
• 645393-23-3 N-(2-bromoethyl)-N-(1-ethoxycarbonyl)-4-chlorobenzenesulfonamide 
• 141286-68-2 methyl 4-[2-(4-chlorophenylsulfonylamino)ethylthio]-2,6-difluorophenoxyacetate 
• 151389-60-5 4-Chloro-N-[2-(3,5-difluoro-4-hydroxy-phenylsulfanyl)-ethyl]-benzenesulfonamide 
• 169298-35-5 4-<2-(4-chlorophenylsulfonylamino)ethylthio>-2-fluorophenol 

Relevant articles and documents

Identifying new lead structures to enhance tolerance towards drought stress via high-throughput screening giving crops a quantum of solace

Novel synthetic lead structures interacting with RCAR/(PYR/PYL) receptor proteins were identified based on the results of a high-throughput screening campaign of a large compound library followed by focused SAR studies of the three most promising hit clusters. Whilst indolinylmethyl sulfonamides 8y,z and phenylsulfonyl ethylenediamines 9y,z showed strong affinities for RCAR/ (PYR/PYL) receptor proteins in wheat, thiotriazolyl acetamides 7f,s exhibited promising efficacy against drought stress in vivo (wheat, corn and canola) combined with confirmed target interaction in wheat and arabidopsis thaliana. Remarkably, binding affinities of several representatives of 8 and 9 were on the same level or even better than the essential plant hormone abscisic acid (ABA).

Carbazole-Containing Sulfonamides as Cryptochrome Modulators

The subject matter herein is directed to carbazole-containing sulfonamide derivatives and pharmaceutically acceptable salts or hydrates thereof of structural formula I wherein the variable R1, R2, R3, R4, R5, R6, R7, A, B, C, D, E, F, G, H, a, and b are accordingly described. Also provided are pharmaceutical compositions comprising the compounds of formula I to treat a Cry-mediated disease or disorder, such as diabetes, obesity, metabolic syndrome, Cushing's syndrome, and glaucoma.