151418-47-2Relevant articles and documents
Total Synthesis of Novel 6-Substituted Lavendamycin Antitumor Agents
Seradj, Hassan,Cai, Wen,Erasga, Noe O.,Chenault, Darrell V.,Knuckles, Kathryn A.,Ragains, Justin R.,Behforouz, Mohammad
, p. 473 - 476 (2004)
(Equation presented) Novel 6-substituted lavendamycins have been synthesized for the first time. The key step in these syntheses is a Pictet-Spengler condensation (Scheme 1). Efficient methods for the synthesis of each compound, including a novel reaction for the facile introduction of alkylamino groups at the C-6 position of the lavendamycin system, are discussed. Possible mechanisms for these reactions are also presented.
Lavendamycin analogues and methods of synthesizing and using lavendamycin analogues
-
Page/Page column 6; 7; 17, (2010/10/20)
Lavendamycin analogues, methods for their synthesis, and methods for their use in the treatment of diseases such as cancer and HIV infection are described.