151504-81-3

Basic information

• Product Name: Methyl 4-fluoro-2-nitrobenzoate
• Synonyms: Methyl 4-fluoro-2-nitrobenzoate;Benzoic acid, 4-fluoro-2-nitro-, Methyl ester;5-Fluoro-2-(methoxycarbonyl)nitrobenzene
• CAS NO: 151504-81-3
• Molecular Formula: C₈H₆FNO₄
• Molecular Weight: 199.14
• Product Categories: blocks;Carboxes;FluoroCompounds;NitroCompounds
• Mol File: 151504-81-3.mol

Chemical Properties

• Boiling Point: 272.1 °C at 760 mmHg
• Flash Point: 118.4 °C
• Appearance: /
• Density: 1.388 g/cm³
• Vapor Pressure: 0.00619mmHg at 25°C
• Refractive Index: 1.533
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl 4-fluoro-2-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-fluoro-2-nitrobenzoate(151504-81-3)
• EPA Substance Registry System: Methyl 4-fluoro-2-nitrobenzoate(151504-81-3)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 151504-81-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 4-fluoro-2-nitrobenzoate is used as a key building block in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with improved therapeutic properties and reduced side effects.
Used in Agrochemical Industry:
In the agrochemical industry, Methyl 4-fluoro-2-nitrobenzoate serves as an essential intermediate in the production of various agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness in controlling pests and weeds, thereby improving crop yields and food security.
Used in Dye and Pigment Industry:
Methyl 4-fluoro-2-nitrobenzoate is utilized as an intermediate in the synthesis of dyes and pigments, contributing to the development of new colorants with improved properties, such as higher color strength, better lightfastness, and increased stability.
Used in Organic Compounds Synthesis:
As a versatile intermediate, Methyl 4-fluoro-2-nitrobenzoate is employed in the synthesis of a wide range of organic compounds, including polymers, resins, and other specialty chemicals. Its unique structure allows for the creation of novel materials with specific properties tailored to various applications.
Safety Precautions:
Due to its potentially hazardous nature, Methyl 4-fluoro-2-nitrobenzoate should be handled and stored with appropriate safety measures. This includes wearing personal protective equipment, such as gloves and goggles, and following proper disposal and containment procedures to minimize the risk of exposure and environmental contamination.

InChI:InChI=1/C8H6FNO4/c1-14-8(11)6-3-2-5(9)4-7(6)10(12)13/h2-4H,1H3

Upstream product

• 42087-80-9 methyl 4-chloro-2-nitrobenzoate 
• 67-56-1 methanol 
• 394-01-4 4-fluoro-2-nitrobenzoic acid 
• 74-88-4 methyl iodide 
• 18959-17-6 2,4-dinitro-benzoic acid methyl ester 

Downstream Products

• 773874-70-7 methyl 4-(dimethylamino)-2-nitrobenzoate 
• 713511-19-4 4-(3-fluoro-benzyloxy)-2-nitro-benzoic acid methyl ester 
• 713511-18-3 4-(3-fluoro-benzyloxy)-2-nitro-benzoic acid (3-fluoro-benzyl) ester 
• 1072915-72-0 methyl 4-[3-(3,5-dichlorophenyl)-3-(trifluorornethyl)pyrrolidin-1-yl]-2-nitrobenzoate 
• 1447084-29-8 methyl 2-nitro-4-phenoxybenzoate 
• 1431382-14-7 C₁₇H₁₂BrNO₅S₂ 
• 1431382-18-1 C₂₀H₁₇NO₅S 
• 1431382-19-2 C₁₉H₁₃BrFNO₅S 
• 1431382-15-8 C₁₄H₁₃NO₃*ClH 
• 1447084-49-2 C₁₈H₁₄BrNO₅S₂ 
• 1447084-68-5 C₂₁H₁₉NO₅S 
• 1447084-88-9 C₂₀H₁₅BrFNO₅S 

Relevant articles and documents

MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO

This disclosure relates to compounds having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such compounds and intermediates used in such processes, compositions containing such compounds, and processes of using such compounds against such pests. These compounds/molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses compounds having the following formula (Formula One and/or Formula One-A).

QUINAZOLINEDIONE DERIVATIVE

The present invention relates to quinazolinedione derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.

3H-QUINAZOLIN-4-ONE DERIVATIVES

This invention relates to 3H-quinazolin-4-one derivatives as defined in the specification and claims, to a process for their preparation, to pharmaceutical compositions comprising them and to their use as selective monoamine oxidase B inhibitors.

Methylhexamethylenetetramine fluoride dihydrate: A new fluorodenitration reagent

Methylhexamethylenetetramine fluoride dihydrate has been prepared by conventional methods. It is moderately soluble in polar aprotic solvents, and shows good thermal stability, enabling it to be dried. The reagent is capable of converting activated nitroaromatics to the corresponding fluoroaromatics, with a high selectivity to monofluorodenitration being observed with some polysubstituted aromatics.

Selective fluorodenitration of chloronitroaromatics

Nucleophilic fluorination of chloronitrobenzenes shows a strong bias for fluorodenitration rather than halogen exchange.

Fluorodenitrations using Tetramethylammonium Fluoride

Tetramethylammonium fluoride activated by azeotropic drying in situ is an efficient reagent for the fluorodenitration of nitroaromatics.