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151539-64-9

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151539-64-9 Usage

General Description

1-(2-carboxyethenyl)-4-methoxynaphthalene is a chemical compound with the molecular formula C14H12O3. It is a derivative of naphthalene and contains a carboxyethenyl group and a methoxy group. 1-(2-carboxyethenyl)-4-methoxynaphthalene is commonly used as a fluorescent dye in biological and chemical research, as it can be used to label specific molecules in cells and tissues for visualization under a microscope. It is also used in the production of pharmaceuticals and as a chemical intermediate in organic synthesis. Additionally, it has potential applications in the development of new materials for electronics and optoelectronics due to its unique optical and electronic properties. However, it is important to handle this compound with care, as it may have harmful effects on human health and the environment if not properly managed.

Check Digit Verification of cas no

The CAS Registry Mumber 151539-64-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,5,3 and 9 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 151539-64:
(8*1)+(7*5)+(6*1)+(5*5)+(4*3)+(3*9)+(2*6)+(1*4)=129
129 % 10 = 9
So 151539-64-9 is a valid CAS Registry Number.

151539-64-9Relevant articles and documents

Evaluation of synthetic naphthalene derivatives as novel chemical chaperones that mimic 4-phenylbutyric acid

Mimori, Seisuke,Koshikawa, Yukari,Mashima, Yu,Mitsunaga, Katsuyoshi,Kawada, Koichi,Kaneko, Masayuki,Okuma, Yasunobu,Nomura, Yasuyuki,Murakami, Yasuoki,Kanzaki, Tetsuto,Hamana, Hiroshi

, p. 811 - 814 (2015/02/19)

The chemical chaperone 4-phenylbutyric acid (4-PBA) has potential as an agent for the treatment of neurodegenerative diseases. However, the requirement of high concentrations warrants chemical optimization for clinical use. In this study, novel naphthalene derivatives with a greater chemical chaperone activity than 4-PBA were synthesized with analogy to the benzene ring. All novel compounds showed chemical chaperone activity, and 2 and 5 possessed high activity. In subsequent experiments, the protective effects of the compounds were examined in Parkinson's disease model cells, and low toxicity of 9 and 11 was related to amphiphilic substitution with naphthalene.

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