151668-40-5

Usage

Uses

Used in Pharmaceutical Industry:
2-(trifluoroMethyl)-4H-chroMen-4-one is used as a pharmaceutical intermediate for the development of new drugs. Its unique structure and trifluoromethyl substituent can contribute to the enhancement of drug properties, such as potency, selectivity, and metabolic stability.
Used in Agrochemical Industry:
2-(trifluoroMethyl)-4H-chroMen-4-one is used as an agrochemical intermediate for the synthesis of new pesticides or other agrochemicals. The trifluoromethyl group can provide specific properties that improve the effectiveness and selectivity of these compounds in agricultural applications.
Used in Research and Development:
2-(trifluoroMethyl)-4H-chroMen-4-one is used as a research compound for studying the effects of trifluoromethyl substitution on the properties and reactivity of chromene derivatives. This can lead to the discovery of new synthetic methods, applications, and insights into the structure-activity relationships of these compounds.

Upstream product

• 78605-60-4 2-hydroxy-2-(trifluoromethyl)chroman-4-one 
• 118-93-4 o-hydroxyacetophenone 
• 407-25-0 trifluoroacetic anhydride 
• 108-95-2 phenol 
• 151668-39-2 2-amino-4-(2-hydroxyphenyl)-1,1,1-trifluoro-2-buten-4-one 

Downstream Products

• 365242-43-9 2-(trifluoromethyl)-1,2-dihydro-4H-thieno[2,3-c]chromen-4-one 
• 1665-65-2 diethyl 2,2'-disulfanediyldiacetate 
• 603131-00-6 2-(2-hydroxyphenyl)-6-(2-methoxyphenyl)-4-(trifluoromethyl)pyridine 
• 125647-92-9 3-chloro-2-(trifluoromethyl)chromone 
• 54216-01-2 N,N'-trimethylenebis(imine) of 2-hydroxyacetophenone 
• 240417-93-0 2-(7-trifluoromethyl-2,3-dihydro-1H-[1,4]diazepin-5-yl)-phenol 
• 1346237-61-3 2-hydroxy-6-(2-hydroxyphenyl)-4-(trifluoromethyl)pyridine-3-carbonitrile 
• 1571088-43-1 3-acetyl-6-(2-hydroxyphenyl)-1-phenyl-4-(trifluoromethyl)pyridin-2(1H)-one 

Relevant academic research and scientific papers

PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES

Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein Q, Z, R2, R3 and m are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.

PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES

Disclosed are compounds of Formula (1), including all stereoisomers, N-oxides, and salts thereof, wherein Q, Z, R2, R3 and m are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (1) and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.

New tetracyclic 1,4-oxazepines constructed via practically simple tandem condensation strategy from readily available synthons

A streamlined synthetic methodology towards novel tetracyclic 1,4-oxazepines from readily available precursors is described. The compounds, designed as more soluble version of the earlier described, poorly soluble dibenzo[b,f][1,4]oxazepines, were obtained in high yields and as a single regioisomer as a result of three tandem chemical events - nucleophilic aromatic substitution, Smiles rearrangement and denitrocyclization.

One-pot synthesis of 2-trifluoromethylchromones

We report a simple and suitable method for the preparation of useful 2-trifluoromethylchromones in one step, in high yields and avoiding the use of solvents. We were able to detect the intermediate of this reaction. Furthermore a mechanism for the formati

Microwave-assisted synthesis of functionalized flavones and chromones

A facile microwave synthesis of functionalized flavones and chromones via the cyclization of 1-(2-hydroxyaryl)-3-aryl-1,3-propanedione is described.

Synthesis of 2-polyfluoroalkylated thiochromones and chromones

A number of 2-(polyfluoroalkyl)-thiochromones (4) and -chromones (5) have been synthesized in good to excellent yield by an intramolecular Friedel-Crafts acylation of the Z isomers of 3-(arylthio)- (2) and 3-(aryloxy)polyfluoro-2-alkenoic acids (3), which

CONDENSATION OF TRICHLORO- AND TRIFLUOROACETONITRILES WITH 4-HYDROXY-4-METHYL-2-PENTANONE AND 2-HYDROXYACETOPHENONE

The condensation of trichloro- and trifluoroacetonitriles with 4-hydroxy-4-methyl-2-pentanone and 2-hydroxyacetophenone in the presence of (phenylethylamino)magnesium bromide gave a series of β-aminovinyl ketones containing a hydroxyl group in addition to the aminoenone system.Acid hydrolysis of these compounds gave high yields of dihydro- and tetrahydropyrans and also chromones and chromanones.