15174-07-9Relevant academic research and scientific papers
A formal synthesis of lavendamycin methyl ester, nitramarine, and their analogues: A povarov approach
Ramesh, Subburethinam,Nagarajan, Rajagopal
, p. 545 - 558 (2013/03/14)
A convergent formal synthesis of lavendamycin methyl ester and synthesis of its analogues have been delineated through the Povarov approach. This protocol is also applied to the formal synthesis of nitramarine (3) in good yield.
Total synthesis of lavendamycin by a [2+2+2] cycloaddition
Nissen, Felix,Detert, Heiner
experimental part, p. 2845 - 2853 (2011/06/26)
The total synthesis of the bacterial-derived, pentacyclic, antitumor antibiotic lavendamycin has been achieved through a highly convergent strategy. The key step of this synthesis is a ruthenium-catalyzed [2+2+2] cycloaddition of an electron-deficient nit
The total synthesis of neoamphimedine
LaBarbera, Daniel V.,Bugni, Tim S.,Ireland, Chris M.
, p. 8501 - 8505 (2008/02/13)
(Chemical Equation Presented) Neoamphimedine, a pyridoacridine alkaloid from Xestospongia sp., is a potent antitumor agent both in vitro and in vivo. Neoamphimedine can efficiently induce topoisomerase II mediated catenation of plasmid DNA in vitro and is
Benzimidazole-4,7-diones as inhibitors of protozoal (Toxoplasma gondii) purine nucleoside phosphorylase
Alvarez, Frédéric,Ghérardi, Arnaud,Nebois, Pascal,Sarciron, Marie-Elizabeth,Pétavy, Anne-Fran?oise,Walchshofer, Nadia
, p. 977 - 979 (2007/10/03)
Benzimidazole-4,7-diones derivatives substituted at 1- and/or 2-position have been synthetized and tested as inhibitors of purine nucleoside phosphorylase (PNP), isolated from two strains of Toxoplasma gondii (RH and ME 49). They were identified as inhibi
