151858-80-9

Upstream product

• 108-24-7 acetic anhydride 
• 151858-78-5 -4-<<2-hydroxy 1-(2-methoxy-6-methylphenyl)ethyl>amino>-4-oxo-2-butenoic acid 
• 127-09-3 sodium acetate 

Downstream Products

• 151858-76-3 (R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-(2-methoxy-6-methyl-phenyl)-ethylamine 
• 151858-75-2 (2R)-2-amino-2-(2-methoxy-6-methylphenyl)ethyl alcohol 

Relevant academic research and scientific papers

The asymmetric synthesis of (-)-quinocarcin via a 1,3-dipolar cycloadditive strategy

Details of the asymmetric synthesis and complete structure elucidation of (-)-quinocarcin (1), an antitumor antibiotic that inhibits DNA (and in some systems RNA) synthesis, are reported. Key steps in the synthesis include the use of an auxiliary-controll