151869-73-7Relevant academic research and scientific papers
Selenazole diphosphonic acid compound and preparation method thereof
-
Paragraph 0025, (2021/01/15)
The invention belongs to the technical field of medicines, and discloses a selenazole diphosphonic acid compound and a preparation method thereof, the structural characteristics of the compound are identified, the selenazole diphosphonic acid compound has
Linking bisphosphonates to the free amino groups in fluoroquinolones: Preparation of osteotropic prodrugs for the prevention of osteomyelitis
Houghton, Tom J.,Tanaka, Kelly S. E.,Kang, Ting,Dietrich, Evelyne,Lafontaine, Yanick,Delorme, Daniel,Ferreira, Sandra S.,Viens, Frederic,Arhin, Francis F.,Sarmiento, Ingrid,Lehoux, Dario,Fadhil, Ibtihal,Laquerre, Karine,Liu, Jing,Ostiguy, Valérie,Poirier, Hugo,Moeck, Gregory,Parr Jr., Thomas R.,Far, Adel Rafai
experimental part, p. 6955 - 6969 (2009/11/30)
Osteomyelitis is an infection located in bone and a notoriously difficult disease to manage, requiring frequent and heavy doses of systemically administered antibiotics. Targeting antibiotics to the bone after systemic administration may provide both grea
Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections
-
Page/Page column 84-85, (2008/12/09)
The present invention relates to phosphonated fluoroquinolones, antibacterial analogs thereof, and methods of using such compounds. These compounds are useful as antibiotics for prevention and/or the treatment of bone and joint infections, especially for the prevention and/or treatment of osteomyelitis.
Herbicidal aza bisphosphonic acids and compositions containing the same
-
, (2008/06/13)
Herbicidal compositions containing a bisphosphonic acid compound of the formula STR1 wherein n is 0, 1, 2, 3, 4, 5 or 6, or an agrochemically acceptable salt or hydrolyzable ester thereof and methods of controlling undesirable plant growth using these bis
Steroid derivatives
-
, (2008/06/13)
Asteroid derivative of the general formula: STR1 wherein X--O-- represents a residue of steroid compound and --A-- represents --CO[NH(CHR1)y --(Y)p --CO]m NH--, --CO--(R2)x --(Z)q --CO--NH--, or --CO--(CH2)n --. A therapeutic agent to osteopathy comprising the above steroid derivative is also provided.
SYNTHESE DE CONJUGUES GEM-BISPHOSPHONIQUES DE DERIVES DE LA CORTISONE
Guervenou, J.,Sturtz, G.
, p. 1 - 14 (2007/10/02)
Some gem-bisphosphonic cortico-steroid conjugates are prepared by esterification between gem-bisphosphonate carboxylic acids and steroid primary alcohols.These original products take place in a biological study about a delivery-targeting concept of active constituents in bone therapy, with the assistance of gem-bisphosphonic building-blocks. Key words: gem-bisphosphonate; gem-bisphosphonic; tetraethyl ethylidene gem-bisphosphonate; corticosteroids; esterification; anti-inflammatory; delivery-targeting concept.
