151895-54-4

Upstream product

• 108-24-7 acetic anhydride 
• 54400-75-8 allyl 2-acetamido-2-deoxy-β-D-glucopyranoside 
• 63064-48-2 allyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside 
• 161686-96-0 allyl 2-acetamido-3,4-di-O-acetyl-6-O-tert-butyldimethylsilyl-2-deoxy-β-D-glucopyranoside 
• 84730-34-7 allyl 2-acetamido-3,4-di-O-acetyl-2-deoxy-β-D-glucopyranoside 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 219814-65-0 methyl (phenyl 5-acetamido-4,7,8-tri-O-acetyl-9-azido-2-thio-3,5,9-trideoxy-D-glycero-β-D-galacto-2-nonulopyranosid)onate 
• 220080-46-6 (4S,5R,6R)-5-Acetylamino-6-((1R,2R)-3-azido-1,2-dihydroxy-propyl)-4-hydroxy-2-phenylsulfanyl-tetrahydro-pyran-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Chemoenzymatic synthesis of an N-acetylneuraminic acid analogue having a carbamoylmethyl group at C-4 as an inhibitor of sialidase from influenza virus

5,9-Diacetamido-2,6-anhydro-O-4-carbamoylmethyl-3,5,9-trideoxy-d-glycero-d-galacto-non-2-enonic acid (1) was synthesized via a key intermediate 2 through the Neu5Ac aldolase [E.C.4.1.3.3]-catalyzed aldol reaction of 2-acetamido-2,6-dideoxy-6-azido-d-glucose with sodium pyruvate operating under alkaline conditions (pH 10.5) in order to accelerate epimerization C-2 of N-acetyl-d-glucosamine (d-GlcNAc) derivatives. Compound 1 showed inhibitory activity against sialidase. Copyright (C) 1998 Elsevier Science Ltd.

Synthesis of α-L-fucopyranosyl disaccharides with thioglycosidic linkages and characterization of α-L-fucosidases from bovine kidney and epididymis by their inhibitory activities

Sulfur-linked disaccharide analogs of three α-L-fucopyranosyl 2-acetamido-2-deoxy-β-D-glucopyranosides and one α-L-fucopyranosyl β-D-galactopyranoside were synthesized by substitution reaction of sulfonates and ring-opening reactions of aziridine as well