151950-84-4

Upstream product

• 35761-83-2 3-iodo-but-2-ene-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 151950-97-9 2-(tert-Butyl-dimethyl-silanyloxy)-1-[(Z)-6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hex-4-enyl]-4-methoxy-benzene 
• 179469-93-3 6-(tert-Butyl-dimethyl-silanyloxy)-7-[(Z)-6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hex-4-enyl]-1,4-dimethoxy-naphthalene 
• 207280-38-4 tert-Butyl-((Z)-3-methyl-hexa-2,5-dienyloxy)-diphenyl-silane 
• 286372-20-1 8-(tert-butyl-dimethyl-silanyloxy)-1-(tert-butyl-diphenyl-silanyloxy)-3,5-dimethyl-6-trimethylsilanyloxy-oct-2-en-4-ol 
• 413192-98-0 2-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hex-4-en-3-ol 
• 413193-02-9 2-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hex-4-en-3-ol 
• 413194-08-8 (4-methoxy-phenyl)-carbamic acid 1-[1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-(tert-butyl-diphenyl-silanyloxy)-2-methyl-but-2-enyl ester 
• 1590412-98-8 (Z)-[4′-²H₃]-tert-butyl((3-methylbut-2-en-1-yl)oxy)diphenylsilane 
• 151950-87-7 Trifluoro-methanesulfonic acid 2-[(Z)-6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hex-4-enyl]-phenyl ester 
• 151950-98-0 tert-Butyl-[(E)-2-((S)-1-methyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-vinyloxy]-diphenyl-silane 
• 151950-92-4 Trifluoro-methanesulfonic acid 2-[(Z)-6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hex-4-enyl]-5-methoxy-phenyl ester 
• 179469-94-4 Trifluoro-methanesulfonic acid 3-[(Z)-6-(tert-butyl-diphenyl-silanyloxy)-4-methyl-hex-4-enyl]-5,8-dimethoxy-naphthalen-2-yl ester 
• 221056-83-3 C₃₇H₅₀O₅Si 

Relevant academic research and scientific papers

δ-deuterium isotope effects as probes for transition-state structures of isoprenoid substrates

The biosynthetic pathways to isoprenoid compounds involve transfer of the prenyl moiety in allylic diphosphates to electron-rich (nucleophilic) acceptors. The acceptors can be many types of nucleophiles, while the allylic diphosphates only differ in the number of isoprene units and stereochemistry of the double bonds in the hydrocarbon moieties. Because of the wide range of nucleophilicities of naturally occurring acceptors, the mechanism for prenyltransfer reactions may be dissociative or associative with early to late transition states. We have measured δ-secondary kinetic isotope effects operating through four bonds for substitution reactions with dimethylallyl derivatives bearing deuterated methyl groups at the distal (C3) carbon atom in the double bond under dissociative and associative conditions. Computational studies with density functional theory indicate that the magnitudes of the isotope effects correlate with the extent of bond formation between the allylic moiety and the electron-rich acceptor in the transition state for alkylation and provide insights into the structures of the transition states for associative and dissociative alkylation reactions.