1520-31-6

Basic information

• Product Name: S,S-dimethyl sulfoximine
• Synonyms: S,S-dimethyl sulfoximine;DiMethylsulfoxiMide;Dimethylsulfoximine;S,S-Dimethylsulfoximide;(Dimethanesulfinylidene)amine;(S-Methylsulphonimidoyl)methane;S,S-Dimethylsulphoximine;(S-methylsulfonimidoyl)methane
• CAS NO: 1520-31-6
• Molecular Formula: C₂H₇NOS
• Molecular Weight: 93.15
• Product Categories: 2018
• Mol File: 1520-31-6.mol
• Article Data: 23

Chemical Properties

• Melting Point: 56 °C
• Boiling Point: 105℃
• Flash Point: 18℃
• Appearance: /
• Density: 1.13
• Vapor Pressure: 34.4mmHg at 25°C
• Refractive Index: 1.454
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: S,S-dimethyl sulfoximine(CAS DataBase Reference)
• NIST Chemistry Reference: S,S-dimethyl sulfoximine(1520-31-6)
• EPA Substance Registry System: S,S-dimethyl sulfoximine(1520-31-6)

Safety Data

• Hazardous Substances Data: 1520-31-6(Hazardous Substances Data)

Usage

Uses

(dimethanesulfinylidene)amine is a useful reactant for the synthesis of N-?sulfenyl sulfoximines derivatives and as well as useful for N-?thioetherification of NH-?sulfoximines.

InChI:InChI=1/C2H7NOS/c1-5(2,3)4/h3H,1-2H3

Upstream product

• 75-18-3 dimethylsulfide 
• 67-68-5 dimethyl sulfoxide 
• 67-66-3 chloroform 
• 7664-93-9 sulfuric acid 
• 21865-94-1 S,S-dimethyl-N-phthalimidosulfoximine 
• 62995-07-7 Benzyl (dimethyl(oxo)-λ⁶-sulfaneylidene)carbamate 
• 22236-45-9 S,S-dimethyl-N-(4-tolylsulfonyl)sulfoximine 
• 13904-95-5 S,S-dimethylsulfodiimide 
• 748142-64-5 N-acetyl-S,S-dimethylsulfoximine 

Downstream Products

• 1520-06-5 C₁₁H₁₆N₂O₃S 
• 32617-70-2 C₉H₁₃NO₂S₂ 
• 1520-09-8 S,S-dimethyl-N-[(3-nitrophenyl)carbamoyl]sulphoximide 
• 1520-32-7 C₁₀H₁₁BrN₂O₂S₂ 
• 1520-18-9 C₁₀H₁₄N₂O₂S 
• 1520-02-1 C₉H₁₁ClN₂O₂S 
• 1520-00-9 C₉H₁₁ClN₂O₂S 
• 1520-03-2 C₉H₁₀Cl₂N₂O₂S 
• 1520-08-7 C₉H₁₁N₃O₄S 
• 1520-10-1 S,S-dimethyl-N-[(4-nitrophenyl)carbamoyl]sulphoximide 
• 31280-33-8 N-(benzoyl)-S,S-dimethylsulfoximine 
• 1519-99-9 C₉H₁₂N₂O₂S 
• 1520-34-9 1-(Dimethylsuloxyliden)-3-phenylthioharnstoff 
• 1520-19-0 C₁₀H₁₄N₂O₂S 

Relevant articles and documents

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Nickel-Catalyzed N-Arylation of NH-Sulfoximines with Aryl Halides via Paired Electrolysis

A novel strategy for the N-arylation of NH-sulfoximines has been developed by merging nickel catalysis and electrochemistry (in an undivided cell), thereby providing a practical method for the construction of sulfoximine derivatives. Paired electrolysis is employed in this protocol, so a sacrificial anode is not required. Owing to the mild reaction conditions, excellent functional group tolerance and yield are achieved. A preliminary mechanistic study indicates that the anodic oxidation of a NiII species is crucial to promote the reductive elimination of a C?N bond from the resulting NiIII species at room temperature.

BIARYL DERIVATIVE, PREPARATION METHOD THEREOF AND PHARMACEUTICAL APPLICATION THEREOF

Disclosed are a biaryl derivative having a structure represented by Formula (I) and inhibitory activity against PD-1/PD-L1 interaction, a preparation method thereof, and a pharmaceutical application thereof. The series of compounds of the present inventio

HETEROCYCLIC INHIBITORS OF ATR KINASE

The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of ATR kinase for the treatment or prevention of cancer.