1520087-38-0

Basic information

• Product Name: 4-(4-chlorophenyl)-2-(p-tolyl)quinazoline
• Synonyms: 4-(4-chlorophenyl)-2-(p-tolyl)quinazoline
• CAS NO: 1520087-38-0
• Molecular Weight: 330.816
• Mol File: 1520087-38-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(4-chlorophenyl)-2-(p-tolyl)quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-chlorophenyl)-2-(p-tolyl)quinazoline(1520087-38-0)
• EPA Substance Registry System: 4-(4-chlorophenyl)-2-(p-tolyl)quinazoline(1520087-38-0)

Safety Data

• Hazardous Substances Data: 1520087-38-0(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 5439-98-5 2-phenyl-2,3-dihydro-phthalazine-1,4-dione 
• 18818-41-2 2-(4-methylphenyl)-4(3H)-quinazolinone 
• 1679-18-1 4-Chlorophenylboronic acid 

Relevant articles and documents

Ru(II)-Catalyzed C-H Activation and Annulation Reaction via Carbon-Carbon Triple Bond Cleavage

An unprecedented Ru(II)-catalyzed C-H activation and annulation reaction, which proceeds via C-C triple bond cleavage, is reported. This reaction of 2-phenyldihydrophthalazinediones with alkynes, which works most efficiently in the presence of bidented ligand 1,3-bis(diphenylphosphino)propane, affords good yields of substituted quinazolines.

Synthesis of 4-arylquinazolines by arylation of quinazolin-4-ones under mild conditions

An efficient route to 4-arylquinazolines via arylation of quinazolin-4-ones under mild condition is described. The reaction is carried out by the palladium-catalyzed coupling of quinazolin-4-ones with arylboronic acids in the presence of TsCl leading to 4-arylquinazolines in good to excellent yields. Georg Thieme Verlag Stuttgart New York.