152099-79-1

Basic information

• Product Name: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(3-methoxyphenyl)methyl]-
• CAS NO: 152099-79-1
• Molecular Formula: C12H12N2O4
• Molecular Weight: 248.238
• Mol File: 152099-79-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(3-methoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(3-methoxyphenyl)methyl]-(152099-79-1)
• EPA Substance Registry System: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(3-methoxyphenyl)methyl]-(152099-79-1)

Safety Data

• Hazardous Substances Data: 152099-79-1(Hazardous Substances Data)

Upstream product

• 56504-52-0 5-(3-methoxybenzylidene)pyrimidine-2,4,6-trione 
• 591-31-1 3-methoxy-benzaldehyde 

Downstream Products

• 874961-93-0 5-(3-methoxybenzyl)-6-chloro-1H-pyrimidine-2,4-dione 

Relevant articles and documents

2-Phenyl-2,3-dihydrobenzo[ d ]thiazole: A Mild, Efficient, and Highly Active in situ Generated Chemoselective Reducing Agent for the One-Pot Synthesis of 5-Monoalkylbarbiturates in Water

A metal- and catalyst-free reductive alkylation protocol for the one-pot synthesis of 5-monoalkylbarbiturates from barbituric acids and aldehydes using the in situ generated chemoselective reducing agent 2-phenyl-2,3-dihydrobenzo[ d ]thiazole from 2-aminothiophenol and benzaldehyde is described. The notable advantages of the protocol are operational simplicity, mild reaction conditions, high yield, short reaction time, and simple workup and purification process which make it highly attractive.

Synthesis of a New Class of Uridine Phoshorylase Inhibitors

A new series of potent uridine phosphorylase inhibitors have been prepared from barbituric acid.Among them 1--5-(m-benzyloxy)benzylbarbituric acid (37, BBBA) is the most promising having a Ki value of 1.1 +/- 0.2 nM wit