1521-94-4

Usage

Synonyms

OTBCHA

Chemical class

Synthetic fragrance ingredient

Physical state

Colorless liquid

Odor

Floral, woody

Usage

Used in various household and personal care products such as perfumes, colognes, shampoos, and lotions to impart a pleasant scent

Health effects

Limited information available; caution should be exercised when using products containing this chemical

Environmental impact

Limited information available

Allergenic potential

Identified as a potential allergen; individuals with sensitive skin should be mindful of its presence in products they use

Upstream product

• 84-66-2 Diethyl phthalate 
• 75-16-1 methylmagnesium bromide 
• 70201-54-6 1-(2-(1-methylethoxy)phenyl)ethanone 
• 797806-02-1 1,1-dimethyl-3-methylene-phthalan 
• 118-93-4 o-hydroxyacetophenone 
• 137556-77-5 2-(2-Acetylphenoxy)-2-methylpropanoic acid 
• 55549-01-4 α,α-dimethyl-o-xylene α,α'-diol 
• 1689-09-4 3,3-Dimethyl-3H-isobenzofuran-1-one 
• 917-54-4 methyllithium 

Downstream Products

• 136918-14-4 phthalimide 
• 1689-09-4 3,3-Dimethyl-3H-isobenzofuran-1-one 
• 520-03-6 N-phenylphthalimide 

Relevant academic research and scientific papers

[W(CO)5]-catalyzed endo- or exo-cycloisomerization reactions of 1,1-disubstituted 4-pentyn-1-ols: Experimental and theoretical studies

The [W(CO)5]-catalyzed cycloisomerization reaction of 1,1-disubstituted 4-pentyn-1-ol derivatives has been studied from both, an experimental and theoretical point of view. Three different catalytic systems have been evaluated {preformed [(thf)

Copper-catalyzed aerobic C-C bond cleavage of lactols with N-hydroxy phthalimide for synthesis of lactones

The transformation of cyclic hemiacetals (lactols) into lactones has been achieved by Cu-catalyzed aerobic C-C bond cleavage in the presence of N-hydroxy phthalimide (NHPI). The present process is composed of a multistep sequence including a) formation of exo-cyclic enol ethers by dehydration; b) addition of phthalimide N-oxyl radical to the enol ethers followed by trapping of the resulting C-radicals with molecular oxygen to form peroxy radicals; c) reductive generation of oxy radicals and subsequent β-radical fragmentation to generate lactones.

Photocyclization Reactions. Part 1. Synthesis of Dihydrobenzofuranols Using Photocyclization of 2-Alkoxybenzaldehydes, 2'-Alkoxyacetophenones, 2-Formylphenoxyacetic Acids and 2-Acetylphenoxyacetic Acids

Photocyclization reactions were carried out on 2-alkoxybenzaldehydes 1a-f, 2'-alkoxyacetophenones 2a-h, 2-formylphenoxyacetic acids 1i-l and 2-acetylphenoxyacetic acids 2i-m.Irradiation opf 1a-f and 2a-h in acetonitrile gave the corresponding dihydrobenzofuranols 3, 5 and dihydroisobenzofuranols 4, 6.Using carboxylic acids 1i-l, 2i-m as starting materials, decarboxylation occurred immediately to give the corresponding ethers 1a-d, 2a-e.Further irradiation of the solution afforded dihydrobenzofuranols 3,5 and dihydroisobenzofuranols 4, 6.Substituent effects on photocyclization and reaction pathways are discussed.