1521-94-4

Basic information

• Product Name: 1,3,3-Trimethyl-1,3-dihydroisobenzofuran-1-ol
• Synonyms: 1,3,3-Trimethyl-1,3-dihydroisobenzofuran-1-ol;1,3,3-Trimethyl-1-phthalanol
• CAS NO: 1521-94-4
• Molecular Weight: 0
• Mol File: 1521-94-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3,3-Trimethyl-1,3-dihydroisobenzofuran-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,3-Trimethyl-1,3-dihydroisobenzofuran-1-ol(1521-94-4)
• EPA Substance Registry System: 1,3,3-Trimethyl-1,3-dihydroisobenzofuran-1-ol(1521-94-4)

Safety Data

• Hazardous Substances Data: 1521-94-4(Hazardous Substances Data)

Usage

General Description

1,3,3-Trimethyl-1,3-dihydroisobenzofuran-1-ol, also known as OTBCHA, is a synthetic fragrance ingredient used in various household and personal care products. It is a colorless liquid with a floral, woody odor. OTBCHA is typically added to products such as perfumes, colognes, shampoos, and lotions to impart a pleasant scent. However, there is limited information available on its potential health effects and environmental impact, so caution should be exercised when using products containing this chemical. Additionally, OTBCHA has been identified as a potential allergen, so individuals with sensitive skin should be mindful of its presence in products they use.

Upstream product

• 70201-54-6 1-(2-(1-methylethoxy)phenyl)ethanone 
• 797806-02-1 1,1-dimethyl-3-methylene-phthalan 
• 55549-01-4 α,α-dimethyl-o-xylene α,α'-diol 
• 1689-09-4 3,3-Dimethyl-3H-isobenzofuran-1-one 
• 917-54-4 methyllithium 
• 84-66-2 Diethyl phthalate 
• 75-16-1 methylmagnesium bromide 
• 137556-77-5 2-(2-Acetylphenoxy)-2-methylpropanoic acid 
• 118-93-4 o-hydroxyacetophenone 

Downstream Products

• 136918-14-4 phthalimide 
• 1689-09-4 3,3-Dimethyl-3H-isobenzofuran-1-one 
• 520-03-6 N-phenylphthalimide 

Relevant articles and documents

[W(CO)5]-catalyzed endo- or exo-cycloisomerization reactions of 1,1-disubstituted 4-pentyn-1-ols: Experimental and theoretical studies

The [W(CO)5]-catalyzed cycloisomerization reaction of 1,1-disubstituted 4-pentyn-1-ol derivatives has been studied from both, an experimental and theoretical point of view. Three different catalytic systems have been evaluated {preformed [(thf)

Photocyclization Reactions. Part 1. Synthesis of Dihydrobenzofuranols Using Photocyclization of 2-Alkoxybenzaldehydes, 2'-Alkoxyacetophenones, 2-Formylphenoxyacetic Acids and 2-Acetylphenoxyacetic Acids

Photocyclization reactions were carried out on 2-alkoxybenzaldehydes 1a-f, 2'-alkoxyacetophenones 2a-h, 2-formylphenoxyacetic acids 1i-l and 2-acetylphenoxyacetic acids 2i-m.Irradiation opf 1a-f and 2a-h in acetonitrile gave the corresponding dihydrobenzofuranols 3, 5 and dihydroisobenzofuranols 4, 6.Using carboxylic acids 1i-l, 2i-m as starting materials, decarboxylation occurred immediately to give the corresponding ethers 1a-d, 2a-e.Further irradiation of the solution afforded dihydrobenzofuranols 3,5 and dihydroisobenzofuranols 4, 6.Substituent effects on photocyclization and reaction pathways are discussed.