15210-14-7

Upstream product

• 108-94-1 cyclohexanone 
• 1125-99-1 1-(1-Cyclohexen-1-yl)pyrrolidine 
• 100846-73-9 2-(2-oxo-cyclohexyl)-propionic acid 
• 360055-41-0 ethyl 2-(2-oxocyclohexyl)propanoate 
• 1919-00-2 4,5,6,7-tetrahydro-3-methylbenzofuran 
• 15174-78-4 2,4,5,6,7,7a-Hexahydro-3-methyl-1-benzofuran-2-on 
• 862015-57-4 tert-butyl-dimethyl-(3-methyl-4,5,6,7-tetrahydro-benzofuran-2-yloxy)-silane 
• 591231-64-0 trimethyl(3-methyl-4,5,6,7-tetrahydro-benzofuran-2-yl)silane 
• 15210-00-1 acide α-(ceto-2 cyclohexyle)-lactique 
• 127-17-3 2-oxo-propionic acid 

Relevant academic research and scientific papers

Regioselectivity of dimerisation of butenolides via captodative stabilised radicaloid intermediates

The regioselective outcome observed during dimerisation of butenolides to dimeric structures via captodative stabilised radicaloids has been studied. The captodative stabilised radicaloids were generated by initial conversion of butenolides to chlorobutenolides via the corresponding hydroxybutenolides, followed by treatment with CoCl(PPh3)3.

1,6-Additionen an 3-Methyl-5-methyliden-2(5H)-furanon-Derivate

The anions of thiophenol, methyl malonate and malononitrile react with 3-methyl-5,6-dihydro-2(4H)-benzofuranone (1c) by the formation of the corresponding 1,6-addition products cis-5c (63percent), trans-6 (42percent) and trans-7 (76percent), respectively.

Dimerization of butenolide structures. A biomimetic approach to the dimeric sesquiterpene lactones (±)-biatractylolide and (±)- biepiasterolide

The biomimetic synthesis of the bisesquiterpene lactones (±)-biatractylolide 1 and (±)-biepiasterolide 2 via dimerization of the captodative stabilized radical 8 is reported. Atractylon 7 has also been shown to be a possible intermediate during the biosynthesis of biatractylolide 1, biepiasterolide 2, atractylolide 3, and hydroxyatractylolide 4.

Studies towards the biomimetic synthesis of bisesquiterpene lactones

A possible biomimetic connection between atractylolide, hydroxyatractylolide and biatractylolide and biepiasterolide has been demonstrated by efficiently generating the biatractylolide and biepiasterolide core structures from atractylolide and hydroxyatra

Analogues of the Histamine Liberating Dihydroxysesquiterpene Lactone Thapsigargin. Synthesis, X-Ray Analysis and Chemistry

Racemic modifications of three isomeric 3-methyl-3,3a-dihydroxyhexahydrobenzofuran-2-ones and three isomeric 3-methyl-3,3a-dihydroxyoctahydrocycloheptafuran-2-ones were prepared via sterospecific oxidation of the corresponding α,β-unsaturated lactones