152140-55-1

Basic information

• Product Name: (R)-(-)-1,3-diphenylpent-4-ene-1-one
• Synonyms: (R)-(-)-1,3-diphenylpent-4-ene-1-one
• CAS NO: 152140-55-1
• Molecular Weight: 236.313
• Mol File: 152140-55-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: (R)-(-)-1,3-diphenylpent-4-ene-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-1,3-diphenylpent-4-ene-1-one(152140-55-1)
• EPA Substance Registry System: (R)-(-)-1,3-diphenylpent-4-ene-1-one(152140-55-1)

Safety Data

• Hazardous Substances Data: 152140-55-1(Hazardous Substances Data)

Upstream product

• 917-57-7 vinyllithium 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 309944-81-8 cinnamyl 3-oxo-3-phenylpropanonate 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 2687-12-9 cinnamyl chloride 
• 673-32-5 1-Phenylprop-1-yne 
• 98-86-2 acetophenone 
• 4393-06-0 1-Phenyl-2-propen-1-ol 
• 697301-71-6 (1-phenylvinyl)carbamic acid benzyl ester 
• 857489-17-9 N-(1-phenylethenyl)benzamide 
• 120-46-7 1,3-diphenylpropanedione 
• 614-20-0 3-oxo-3-phenylpropionic acid 
• 100-52-7 benzaldehyde 
• 143705-80-0 (E)-3-phenylprop-2-en-1-yl 3-oxo-3-phenylpropanoate 

Downstream Products

• 16460-86-9 (S)-1,3-diphenylpentan-1-one 

Relevant articles and documents

Iridium-catalyzed enantioselective allylation of aryl enamides and enecarbamates

Aromatic enamide and enecarbamate as a novel type of nucleophile in the asymmetric allylation of branched, racemic allylic alcohols to give homoallylic ketones has been described. Enabled by Carreira's chiral Ir (P, olefin) complex, the reactions proceed

Rhodium-Catalyzed Branched and Enantioselective Direct α-Allylic Alkylation of Simple Ketones with Alkynes

Herein, we report the first direct branched-selective α-allylic alkylation of simple ketones with alkynes under rhodium and secondary amine cooperative catalysis. Through a rhodium-hydride-catalyzed allylic substitution pathway, a series of valuable γ,δ-unsaturated ketones are obtained with excellent regioselectivity in an atom-economic and byproduct-free manner. With a chiral BIPHEP ligand, high enantioselectivity has been achieved for this transformation.

Tandem Rh-catalysis: Decarboxylative β-keto acid and alkyne cross-coupling

Herein, we describe a regioselective Rh-catalyzed decarboxylative cross-coupling of β-keto acids and alkynes to access branched γ,δ-unsaturated ketones. Rh-hydride catalysis enables the isomerization of an alkyne to generate a metal-allyl species that can undergo carbon-carbon bond formation. Ketones are generated under mild conditions, without the need for base or activated electrophiles.