180595-86-2

Upstream product

• 152835-59-1 ethyl 3,5-difluoro-6-(N-ethoxycarbonyl-N-pivaloylamino)-2-methoxymethoxybenzoate 
• 3282-30-2 pivaloyl chloride 
• 1026982-73-9 N-(2-{3-[4-(2,2-Dimethyl-propionylamino)-3,5-difluoro-phenyl]-3-oxo-propionyl}-4,6-difluoro-3-methoxymethoxy-phenyl)-2,2-dimethyl-propionamide 
• 152169-42-1 ethyl 3,5-difluoro-6-(N-ethoxycarbonylamino)-2-methoxymethoxybenzoate 
• 152169-41-0 ethyl 3,5-difluoro-6-(N-ethoxycarbonylamino)-2-hydroxybenzoate 
• 152169-36-3 ethyl 6-(N-ethoxycarbonylamino)-2-hydroxybenzoate 
• 130600-32-7 N-(4-Acetyl-2,6-difluoro-phenyl)-2,2-dimethyl-propionamide 
• 811799-69-6 1-(4-amino-3,5-difluorophenyl)ethan-1-one 
• 146463-87-8 ethyl 2-(N-ethoxycarbonyl-N-pivaloyl)amino-6-(tetrahydropyran-2-yloxy)benzoate 

Relevant academic research and scientific papers

Design and synthesis of potent antitumor 5,4'-diaminoflavone derivatives based on metabolic considerations

Recently, we reported that 5,4'-diaminoflavone (1) exhibits potent and specific growth-inhibitory activity against the estrogen receptor (ER)- positive human breast cancer cell line MCF-7. However, when compound 1 was incubated with S-9 mix, its metabolit

5-aminoflavone derivatives

5-Aminoflavone derivatives represented by the formula (I): STR1 wherein R1, R2, R3 and R4 are the same or different and represent hydrogen, substituted or unsubstituted lower alkyl, lower alkenyl, halogen-substi