1522363-75-2

Upstream product

• 104-86-9 4-chlorobenzylamine 
• 1522363-55-8 3-(4-chlorobenzylamino)-2,2-dimethyl-3-oxopropyl 2,2,2-trifluoroacetate 
• 120226-55-3 N-pivaloyl-p-chlorophenylmethylamine 
• 3282-30-2 pivaloyl chloride 

Relevant academic research and scientific papers

Palladium-catalyzed β-acyloxylation of simple amide via sp3 C-H activation

β-Acyloxy amides are prepared in moderate to high yields by palladium-catalyzed acyloxylation of primary sp3 C-H bonds from simple amides without any special directing group. A catalytic system of Pd(OAc)2/CF3CO2H/ K2S2O8 is available to various amides with N-substituted by linear alkanes, cyclic alkanes, and electron-deficient benzyl compounds in this reaction. Acyloxylated products could be transformed easily to the corresponding β-hydroxy amides.