152302-59-5

Basic information

• Product Name: (+/-)-3-Methyl-5-phenyl-5H-thiazolo[2,3-b]quinazoline
• Synonyms: (+/-)-3-Methyl-5-phenyl-5H-thiazolo[2,3-b]quinazoline
• CAS NO: 152302-59-5
• Molecular Weight: 278.378
• Mol File: 152302-59-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (+/-)-3-Methyl-5-phenyl-5H-thiazolo[2,3-b]quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-3-Methyl-5-phenyl-5H-thiazolo[2,3-b]quinazoline(152302-59-5)
• EPA Substance Registry System: (+/-)-3-Methyl-5-phenyl-5H-thiazolo[2,3-b]quinazoline(152302-59-5)

Safety Data

• Hazardous Substances Data: 152302-59-5(Hazardous Substances Data)

Upstream product

• 63917-28-2 3,4-dihydro-4-phenyl-2(1H)-quinazolinethione 
• 78-95-5 chloroacetone 
• 13209-38-6 (2-aminophenyl)(phenyl)methanol 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 

Relevant articles and documents

An efficient synthesis of enantiopure SDZ 267-489 via a resolution/racemization method

A new synthesis of (R)-3-methyl-5-phenyl-5H-thiazolo[2,3-b]quinazoline 1, a serum HDL cholesterol raising agent, is described utilizing a resolution of the racemic compound with D-tartaric acid. The undesired S-enantiomer was recycled using either a photochemical or thermal electrocyclic ring opening/closing reaction making the synthesis economical.