13209-38-6

Basic information

• Product Name: 2-AMINOBENZHYDROL
• Synonyms: 2-AMINOBENZHYDROL;(2-AMINOPHENYL)(PHENYL)METHANOL;A-O-AMINOPHENYLBENZYL ALCOHOL;O-AMINOBENZHYDROL;O-AMINODIPHENYLCARBINOL;2-Amino-α-phenylbenzyl alcohol;Phenyl(2-aminophenyl)methanol;α-Phenyl-2-aminobenzyl alcohol
• CAS NO: 13209-38-6
• Molecular Formula: C₁₃H₁₃NO
• Molecular Weight: 199.25
• Product Categories: Benzhydrols, Benzyl & Special Alcohols
• Mol File: 13209-38-6.mol
• Article Data: 33

Chemical Properties

• Melting Point: 114-116°C
• Boiling Point: 387.8 °C at 760 mmHg
• Flash Point: 188.3 °C
• Appearance: /
• Density: 1.176 g/cm³
• Vapor Pressure: 1.04E-06mmHg at 25°C
• Refractive Index: 1.644
• Storage Temp.: 2-8°C
• PKA: 13.40±0.20(Predicted)
• CAS DataBase Reference: 2-AMINOBENZHYDROL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINOBENZHYDROL(13209-38-6)
• EPA Substance Registry System: 2-AMINOBENZHYDROL(13209-38-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 13209-38-6(Hazardous Substances Data)

Usage

General Description

2-aminobenzhydrol, also known as benzhydrolamine, is a chemical compound containing a benzene ring with an amino group and a hydroxyl group. It is often used in the synthesis of pharmaceuticals and as an intermediate in organic chemical reactions. 2-AMINOBENZHYDROL has both hydrophilic and hydrophobic properties, making it useful for various applications, including as a stabilizer in pharmaceutical preparations and as a reducing agent in organic synthesis. It is also a key building block for the production of dyes and pigments in the chemical industry. Additionally, 2-aminobenzhydrol has demonstrated potential anti-inflammatory and antioxidant properties, making it an area of interest for further research in the development of therapeutic agents.

InChI:InChI=1/C13H13NO/c14-12-9-5-4-8-11(12)13(15)10-6-2-1-3-7-10/h1-9,13,15H,14H2/t13-/m1/s1

Upstream product

• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 100-52-7 benzaldehyde 
• 62-53-3 aniline 
• 1885-29-6 anthranilic acid nitrile 
• 100-58-3 phenylmagnesium bromide 
• 529-23-7 o-aminobenzaldehyde 
• 5176-12-5 (2-nitrophenyl)phenylmethanol 
• 552-89-6 2-nitro-benzaldehyde 
• 88092-64-2 2-Acetylamino-3,5-dibromobenzophenone 
• 69751-74-2 (2-amino-3,5-dibromophenyl)phenylmethanone 
• 2243-79-0 2-nitrobenzophenone 
• 7500-78-9 o-benzoylbenzamide 
• 106795-87-3 N-deuterio-o-bromoformanilide 
• 10113-38-9 N-(2-bromophenyl)formamide 

Downstream Products

• 63917-28-2 3,4-dihydro-4-phenyl-2(1H)-quinazolinethione 
• 110150-59-9 2-[α-(toluene-4-sulfonyl)-benzyl]-aniline 
• 107289-02-1 3,4-dihydro-4-phenyl-2-quinazolinone 
• 52744-59-9 phenyl-(4-phenyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-yl)-acetonitrile 
• 3456-79-9 3-phenyloxindole 
• 274917-70-3 2-azido-α-phenylbenzyl alcohol 
• 17282-88-1 2-methyl-4-phenyl-quinoline-3-carboxylic acid ethyl ester 
• 1072913-35-9 methyl 2-isopropyl-4-phenylquinoline-3-carboxylate 
• 1072913-50-8 ethyl 2,4-diphenyl-1,4-dihydroquinoline-3-carboxylate 
• 17282-90-5 ethyl 2,4-diphenylquinoline-3-carboxylate 
• 1072913-34-8 ethyl 4-phenyl-2-propylquinoline-3-carboxylate 
• 1238251-77-8 N-(2-(1-hydroxy-1,3-diphenylprop-2-yn-1-yl)phenyl)-4-methylbenzenesulfonamide 
• 1859-71-8 2-(tosylamino)benzophenone 
• 1238252-30-6 6-phenyl-5-tosyl-5,6-dihydroindeno[2,1-b]indole 

Relevant articles and documents

Intramolecular addition of diarylmethanols to imines promoted by KO: T -Bu/DMF: A new synthetic approach to indole derivatives

KOt-Bu/DMF promoted intramolecular addition of diarylmethanols to imines was developed. A series of 2,3-disubstituted indoles was obtained in good yields. A reaction mechanism of radical cyclization and subsequent dehydration is proposed.

In situthermosensitive hybrid mesoporous silica: preparation and the catalytic activities for carbonyl compound reduction

In this study, free-radical polymerisation inside MCM-41 mesopores was examined to expose a construction route for a temperature-responsive switchable polymer-silica nanohybrid material with well-defined porosity. Herein, we introduced a vinyl monomer (N-isopropyl acrylamide), a cross-linker, and an AIBN initiator into the palladium nanoparticle incorporated MCM-41 pore channels using the wet-impregnation method followed byin situradical polymerisation. The structural properties of the synthesised PNIPAM-PdNP-MCM-41 catalyst were analysed by various sophisticated analytical techniques. The temperature switchable nanohybrid catalyst was used to reduce carbonyl compounds to their corresponding alcohols. The catalyst showed high catalytic efficiency and robustness in an aqueous medium at 25 °C. Moreover, the system's polymer layer remarkably boosted catalytic selectivity and activity for carbonyl compound reduction as compared to other controlled catalysts. The suggested switchable system can be employed as a temperature-controllable heterogeneous catalyst and highlights a substitute technique to counter the methodical insufficiency in switchable supported molecular catalytic system production.

Ruthenium complexes of phosphine-amide based ligands as efficient catalysts for transfer hydrogenation reactions

This work presents three mononuclear Ru(ii) complexes of tridentate phosphine-carboxamide based ligands providing a NNP coordination environment. The octahedral Ru(ii) ion shows additional coordination with co-ligands; CO, Cl and CH3OH. All three Ru(ii) complexes were thoroughly characterized including their crystal structures. These Ru(ii) complexes were utilized as catalysts for the transfer hydrogenation of assorted carbonyl compounds, including some challenging biologically relevant substrates, using isopropanol as the hydrogen source. The binding studies illustrated the coordination of the isopropoxide ion by replacing a Ru-ligated chloride ion followed by the generation of the Ru-H intermediate that was isolated and characterized and was found to be involved in the catalysis.