15233-32-6

Upstream product

• 4998-76-9 cyclohexylamine hydrochloride 
• 127099-85-8 N-Cyanoguanidine 
• 108-91-8 cyclohexylamine 

Downstream Products

• 100524-64-9 N-(cyclohexylamino-methyl-[1,3,5]triazin-2-yl)-acetamide 
• 100133-91-3 amino-cyclohexylamino-[1,3,5]triazine-2-carboxylic acid 
• 788-01-2 4-Amino-6-cyclohexylamino-2-trifluormethyl-1,3,5-triazin 
• 645-20-5 N-cyclohexyl-[1,3,5]triazine-2,4-diamine 
• 43074-77-7 6-(4-tert-butyl-benzyl)-N-cyclohexyl-[1,3,5]triazine-2,4-diamine 
• 99191-12-5 N²-cyclohexyl-6-methyl-[1,3,5]triazine-2,4-diyldiamine 

Relevant academic research and scientific papers

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING IMMUNE DISEASES OR INFLAMMATORY DISEASES, CONTAINING BIGUANIDE DERIVATIVE COMPOUND AS ACTIVE INGREDIENT

The present invention relates to a biguanide derivative compound capable of effectively preventing and treating immune diseases. The biguanide-based derivative compound according to the present invention inhibits the generation of IL-17 and TNF-α, which are inflammatory cytokines, increases the activity of regulatory T cells having an immunomodulatory function, and exhibits excellent therapeutic effects in animal models of immune diseases. Accordingly, the biguanide-based derivative compound can be usefully used as an immunosuppressant or a pharmaceutical composition capable of preventing or treating various immune diseases, such as autoimmune diseases, inflammatory diseases, and transplant rejection, caused by the dysregulation of immune responses.