1523541-94-7 Usage
Description
(3R,4S)-1-tert-butyl 3-ethyl 4-hydroxypyrrolidine-1,3-dicarboxylate is a chiral chemical compound belonging to the class of pyrrolidine dicarboxylate esters. It is synthesized through the esterification of the hydroxyl group of pyrrolidine-1,3-dicarboxylic acid with a tert-butyl group and the carboxylic acid group with an ethyl group. This molecule features two stereocenters, 3R and 4S, which give it a unique three-dimensional arrangement that is not superimposable with its mirror image. Its distinct molecular structure and potential biological activity make it a compound of interest in pharmaceutical research and drug development.
Uses
Used in Pharmaceutical Research:
(3R,4S)-1-tert-butyl 3-ethyl 4-hydroxypyrrolidine-1,3-dicarboxylate is used as a chiral building block for the synthesis of various pharmaceutical compounds. Its unique molecular structure and stereochemistry allow for the creation of novel drugs with potential applications in treating different medical conditions.
Used in Drug Development:
In the drug development industry, (3R,4S)-1-tert-butyl 3-ethyl 4-hydroxypyrrolidine-1,3-dicarboxylate is utilized as a key intermediate in the design and synthesis of new drug candidates. Its potential biological activity and versatile chemical properties make it a valuable asset in the development of innovative therapeutic agents.
Used in Chiral Chemistry:
(3R,4S)-1-tert-butyl 3-ethyl 4-hydroxypyrrolidine-1,3-dicarboxylate is employed as a chiral auxiliary in asymmetric synthesis, which is crucial for obtaining enantiomerically pure compounds. Its ability to induce stereoselectivity in chemical reactions is valuable in the production of chiral molecules with specific biological activities.
Used in Material Science:
In the field of material science, (3R,4S)-1-tert-butyl 3-ethyl 4-hydroxypyrrolidine-1,3-dicarboxylate may be used as a component in the development of novel materials with unique properties, such as improved mechanical strength, thermal stability, or biological compatibility, due to its distinctive molecular structure and chirality.
Check Digit Verification of cas no
The CAS Registry Mumber 1523541-94-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,2,3,5,4 and 1 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1523541-94:
(9*1)+(8*5)+(7*2)+(6*3)+(5*5)+(4*4)+(3*1)+(2*9)+(1*4)=147
147 % 10 = 7
So 1523541-94-7 is a valid CAS Registry Number.
1523541-94-7Relevant articles and documents
TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
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Paragraph 00487-00488, (2021/12/08)
The present disclosure relates to compounds which modulate the activity of Toll-like receptor (TLR) proteins, including agonists or activators, partial agonists, and antagonists. Of particular interest of compounds that modulate the activity of TLR2, as well as methods of using such compounds to treat cancer and other disorders associated with a TLR2 pathway.
Synthesis, antimycobacterial and antibacterial activity of fluoroquinolone derivatives containing an 3-alkoxyimino-4-(cyclopropylanimo)methylpyrrolidine moiety
Zhang, Tingting,Shen, Weiyi,Liu, Mingliang,Zhang, Rui,Wang, Minghua,Li, Linhu,Wang, Bin,Guo, Huiyuan,Lu, Yu
, p. 73 - 85 (2015/10/19)
A series of novel fluoroquinolone derivatives containing an 3-alkoxyimino-4-(cyclopropylanimo)methylpyrrolidine moiety were designed, synthesized and evaluated for their biological activity. Our results revealed that 19b2 shows good activity against MTB H
Peptides containing an arginine mimetic for the treatment of bone metabolic disorders, their production, and drugs containing these compounds
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, (2008/06/13)
Arginine mimetic peptides according to Formula I of this application have a stimulating effect on bone formation and are useful for the treatment of bone metabolic disorders.
