152375-53-6

Downstream Products

• 160748-84-5 2-tetrahydropyranyl (4s)-5-(2-cyanoethoxycarbonyl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3-carboxylate 
• 76093-34-0 (+)-(S)-1,4-dihydro-2,6-dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)pyridine-3-carboxylic acid 
• 143167-32-2 2-cyanoethyl (R)-1,4-dihydro-2,6-dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)-3-pyridinecarboxylate 

Relevant academic research and scientific papers

PROTEASE-CATALYZED ENANTIOSELECTIVE SYNTHESIS OF OPTICALLY ACTIVE 1,4-DIHYDROPYRIDINES

The first enantioselective protease-catalyzed hydrolyses of 1,4-dihydropyridine-3,5-dicarboxylic diesters were developed.The monoesters obtained had high optical purity and were useful building blocks which could easily lead to optically active Ca-blockers.

Optically active 1,4-hydropyridine compounds

Optically active 1,4-dihydropyridine derivatives represented by general formula (I), process for preparing compounds (Ic) (in general formula (I) , R1 is a lower alkyl group), process for preparing compounds represented by general formula (II)