Tetrahedron Letters p. 3441 - 3444 (1993)
Update date:2022-08-05
Topics:
Hirose, Yoshihiko
Kariya, Kinya
Sasaki, Ikuharu
Kurono, Yoshiaki
Achiwa, Kazuo
The first enantioselective protease-catalyzed hydrolyses of 1,4-dihydropyridine-3,5-dicarboxylic diesters were developed.The monoesters obtained had high optical purity and were useful building blocks which could easily lead to optically active Ca-blockers.
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