152453-72-0

Upstream product

• 2746-25-0 p-Methoxybenzyl bromide 
• 1287289-41-1 C₁₇H₂₆O₆ 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 79364-35-5 (S)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)but-3-en-1-ol 
• 824-94-2 p-methoxybenzyl chloride 
• 67320-20-1 1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3,3-bis-ethylsulfanyl-propan-1-ol 
• 152453-71-9 (1'S,4R)-4-(3',3'-bisethylthio-1'-p-methoxybenzyloxypropyl)-2,2-dimethyl-1,3-dioxolane 

Downstream Products

• 152453-73-1 <4R-<4R*<αR*(S*),γS*>>>-γ-<(4-methoxyphenyl)methoxy>-2,2-dimethyl-α-(1-methyl-2-propenyl)-1,3-dioxolane-4-propanol 
• 326921-49-7 (1'S,3'Z,4R)-4-(1'-p-methoxybenzyloxyhex-3'-enyl)-2,2-dimethyl-1,3-dioxolane 
• 152453-82-2 <3S-<3α(1R*,2R*,3S*,5R*,6E),4β(1E,3E)>>-1-<(1,1-dimethylethyl)dimethylsilyl>-4-<5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methyl-1,3-pentadienyl>-3-<3-<<(1,1-diphenylethyl)dimethylsilyl>oxy>-1-hydroxy-7-iodo-5-<(4-methoxyphenyl)methoxy>-2-methyl..>. 
• 152453-83-3 <4R-<4α(2E,4E),4aβ,7α(2S*,3E),8β,8aβ>>-1H-imidazole-1-carboxylic acid 5--3-butenyl>-4a,8-dimethyl-2,5-dioxo-2H,5H-pyrano<3,4-e>-1,3-oxazin-4-yl>-4-methyl-2,4-pentadienyl ester 
• 152453-80-0 <2R-(2R*,3R*,5S*,6E)>-3-<<(1,1-dimethylethyl)diphenylsilyl>oxy>-7-iodo-5-<(4-methoxyphenyl)methoxy>-2-methyl-6-heptenoic acid (S)-2-pyridinyl ester 
• 152453-75-3 2,4-dideoxy-3-O-<(1,1-dimethylethyl)diphenylsilyl>-5-O-<(4-methoxyphenyl)methyl>-2-methyl-6,7-O-(1-methylethylidene)-D-allo-heptaldonic acid methyl ester 
• 152453-77-5 2,4-dideoxy-3-O-<(1,1-dimethylethyl)diphenylsilyl>-5-O-<(4-methoxyphenyl)methyl>-2-methyl-6,7-O-(1-methylethylidene)-D-allo-heptaldonic acid 
• 166186-04-5 2,4-dideoxy-3-O-<(1,1-dimethylethyl)diphenylsilyl>-5-O-<(4-methoxyphenyl)methyl>-2-methyl-6,7-O-(1-methylethylidene)-D-allo-heptose 
• 152453-74-2 <4R-<4R*>>-<<1-<2-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-<(4-methoxyphenyl)methoxy>ethyl>-2-methyl-3-butenyl>oxy>(1,1-dimethylethyl)diphenylsilane 
• 152453-78-6 <2R-(2R*,3R*,5S*,6E)>-3-<<(1,1-dimethylethyl)diphenylsilyl>oxy>-7-iodo-5-<(4-methoxyphenyl)methoxy>-2-methyl-6-heptenoic acid methyl ester 
• 166186-05-6 (2R,3R,5S,6R)-3-(tert-Butyl-diphenyl-silanyloxy)-6,7-dihydroxy-5-(4-methoxy-benzyloxy)-2-methyl-heptanoic acid methyl ester 
• 152453-79-7 <2R-(2R*,3R*,5S*,6E)>-3-<<(1,1-dimethylethyl)diphenylsilyl>oxy>-7-iodo-5-<(4-methoxyphenyl)methoxy>-2-methyl-6-heptenoic acid 
• 152453-76-4 3,5-dideoxy-4-O-<(1,1-dimethylethyl)diphenylsilyl>-2-O-<(4-methoxyphenyl)methyl>-5-methyl-L-ribo-hexuronic acid methyl ester 

Relevant academic research and scientific papers

First stereo selective synthesis of 5-O-feruloyl-2-deoxy-D-ribono-γ-lactone

The first stereo selective synthesis of 5-O-feruloyl-2-deoxy-D-ribono-γ-lactone was achieved by coupling reaction of substituted ferulic acid and hydroxy methyl ribono lactone and followed by deprotection of O-PMB. The spectroscopic data were compared with the reported values and a clear indication to the absolute stereochemistry of the natural 5-O-feruloyl-2-deoxy-D-ribono-γ-lactone.

LAULIMALIDE ANALOGS AND USES THEREOF

The present invention provides compounds having formula 1: (I) and pharmaceutically acceptable derivatives thereof, wherein R1-R10, q, t, X0, X1, A, B, D, E, G, J, K, L, M and Z are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of disorders associated with cellular hyperproliferation.

First total synthesis and determination of the absolute configuration of mueggelone

All the four possible stereoisomers of mueggelone, an inhibitor of fish development, were efficiently synthesized in a stereoselective manner starting from D-arabinose, and the absolute configuration was determined to be 9R, 12S, 13S.

First total synthesis of mueggelone

All the four possible stereoisomers of mueggelone, an inhibitor of fish development, were efficiently synthesized in a stereoselective manner starting from D-arabinose, and the absolute configuration was determined to be 9R,12S, 13S. (C) 2000 Elsevier Science Ltd.

Total synthesis of the macrolide antitumor antibiotic lankacidin C

The first total synthesis of natural (-)-lankacidin C (1) has been achieved by a convergent, enantioselective sequence starting from D-arabinose and L-aspartic acid, proceeding through the tricyclic carbamate 15 as an advanced relay intermediate. Specific