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152529-70-9

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152529-70-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 152529-70-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,5,2 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 152529-70:
(8*1)+(7*5)+(6*2)+(5*5)+(4*2)+(3*9)+(2*7)+(1*0)=129
129 % 10 = 9
So 152529-70-9 is a valid CAS Registry Number.

152529-70-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Cyclopentane carboxylic acid (6-amino-2,4-dioxo-3-propyl-1,2,3,4-tetra hydro-pyrimidin-5-yl)-amide

1.2 Other means of identification

Product number -
Other names 6-amino-5-cyclopentylcarboxamido-3-propyluracil

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:152529-70-9 SDS

152529-70-9Relevant articles and documents

Design and synthesis of novel, potent and selective hypoxanthine analogs as adenosine A1receptor antagonists and their biological evaluation

Koul, Summon,Ramdas, Vidya,Barawkar, Dinesh A.,Waman, Yogesh B.,Prasad, Neela,Madadi, Santosh Kumar,Shejul, Yogesh D.,Bonagiri, Rajesh,Basu, Sujay,Menon, Suraj,Reddy, Srinivasa B.,Chaturvedi, Sandhya,Chennamaneni, Srinivas Rao,Bedse, Gaurav,Thakare, Rhishikesh,Gundu, Jayasagar,Chaudhary, Sumit,De, Siddhartha,Meru, Ashwinkumar V.,Palle, Venkata,Chugh, Anita,Mookhtiar, Kasim A.

, p. 1963 - 1975 (2017/03/09)

Multipronged approach was used to synthesize a library of diverse C-8 cyclopentyl hypoxanthine analogs from a common intermediate III. Several potent and selective compounds were identified and evaluated for pharmacokinetic (PK) properties in Wistar rats. One of the compounds 14 with acceptable PK parameters was selected for testing in in vivo primary acute diuresis model. The compound demonstrated significant diuretic activity in this model.

SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS, ITS PREPARATION AND USES THEREOF

-

Page/Page column 49-50, (2011/06/11)

The present invention provides substituted fused pyrimidine compounds of formula (I), their tautomers, polymorphs, stereoisomers, prodrugs, solvates, pharmaceutically acceptable salts, pharmaceutical compositions containing them and methods of treating co

Synthesis of Paraxanthine Analogs (1,7-Disubstituted Xanthines) and Other Xanthines Unsubstituted at the 3-Position: Structure-Activity Relationships at Adenosine Receptors

Mueller, Christa E.,Shi, Dan,Manning, Malcolm,Daly, John W.

, p. 3341 - 3349 (2007/10/02)

Synthetic procedures for the preparation of various 3-unsubstituted xanthines, including paraxanthine analogs (1,7-disubstituted xanthines) and 1,8-disubstituted xanthines, were developed.Sylylation of 1-substituted xanthines followed by alkylation at the 7-position provides a facile route to paraxanthine analogs.Regioselective alkylation of tris(trimethylsilyl)-6-aminouracil provides 3-substituted 6-aminouracils, which are converted to 1,8-disubstituted xanthines by standard procedures.The ring closure of 3-substituted 5-cyclopentanecarboxamido- and 5-(benzoylamino)-6-aminouracils requires drastic reaction conditions.Affinity for brain A1 and A2 adenosine receptors was determined in binding assays for these and other xanthines with substituents in 1-, 3-, 7-, 8-, and 9-positions.Substitution at the 1-position was necessary for high affinity at adenosine receptors. 1,3-Disubstituted xanthines generally had higher affinity than 1,7-disubstituted xanthines. 1,8-Disubstituted xanthines had high affinity for adenosine receptors; some were highly selective for A1 receptors.

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