152568-67-7Relevant academic research and scientific papers
CC-1065 Functional Analogues Possessing Different Electron-Withdrawing Substituents and Leaving Groups: Synthesis, Kinetics, and Sequence Specificity of Reaction with DNA and Biological Evaluation
Wang, Yuqiang,Gupta, Rajan,Huang, Liren,Lown, J. William
, p. 4172 - 4182 (1993)
Antitumor agent CC-1065 functional analogues possessing different electron-withdrawing substituents and leaving groups have been synthesized.The extent and relative rates of DNA cleavage following alkylation by these CPI structures and thermal treatment w
