106014-85-1

Upstream product

• 112089-51-7 diethyl <4-(benzyloxy)-2-nitrophenyl>malonate 
• 79035-13-5 4-benzyloxy-2-nitro-chlorobenzene 
• 106014-83-9 2-[4-(benzyloxy)-2-nitrophenyl]propane-1,3-diol 
• 610-78-6 3-nitro-4-chlorophenol 
• 124-63-0 methanesulfonyl chloride 
• 106014-84-0 2-<2-amino-4-(benzyloxy)phenyl>propane-1,3-diol 
• 10298-80-3 2-chloro-5-methoxynitrobenzene 

Downstream Products

• 112089-54-0 6-(benzyloxy)-2,3-dihydro-1-(methylsulfonyl)-1H-indole-3-methanol acetate 
• 366789-52-8 6-benzyloxy-3-hydroxymethyl-2,3-dihydro-1H-indole 
• 152568-61-1 6-(benzyloxy)-3-(chloromethyl)-1-(methylsulfonyl)indoline 
• 108833-15-4 Methanesulfonic acid (S)-5-benzyloxy-3-{5-[(1H-indole-2-carbonyl)-amino]-1H-indole-2-carbonyl}-8-methyl-1,2,3,6-tetrahydro-pyrrolo[3,2-e]indol-1-ylmethyl ester 
• 108859-64-9 1H-Indole-2-carboxylic acid [2-((S)-5-benzyloxy-1-hydroxymethyl-8-methyl-1,6-dihydro-2H-pyrrolo[3,2-e]indole-3-carbonyl)-1H-indol-5-yl]-amide 
• 101222-80-4 U-71,184 
• 104713-39-5 U-71,185 
• 108867-95-4 ((R)-5-Benzyloxy-3-methanesulfonyl-8-methyl-1,2,3,6-tetrahydro-pyrrolo[3,2-e]indol-1-yl)-methanol 
• 101222-79-1 ((S)-5-Benzyloxy-3-methanesulfonyl-8-methyl-1,2,3,6-tetrahydro-pyrrolo[3,2-e]indol-1-yl)-methanol 
• 108833-14-3 ((S)-5-Benzyloxy-8-methyl-1,2,3,6-tetrahydro-pyrrolo[3,2-e]indol-1-yl)-methanol 
• 89553-54-8 C₁₃H₁₄N₂O₃S 
• 151384-96-2 6-benzyloxy-1-(N-methyl-2-pyrrolecarboxy)-3-methanesulfonyloxymethylindole 
• 151384-95-1 6-benzyloxy-3-hydroxymethyl-1-(N-methyl-2-pyrrolecarboxy)indole 
• 132628-58-1 3-acetoxymethyl-6-benzyloxy-1-t-butoxycarbonyl-2,3-dihydro-1H-indole 

Relevant academic research and scientific papers

AN ALTERNATIVE METHOD FOR SYNTHESIS OF THE CC-1065 PHARMACOPHORE, 1,2,7,7a-TETRAHYDROCYCLOPROPINDOL-4-ONE

The synthesis of the CC-1065 pharmacophore, 2-(1-methylpyrrole-2-carbonyl)-1,2,7,7a-tetrahydrocyclopropindol-4-one (17), is described.The methods reported here provide an alternative route for the synthesis of compounds possessing the biologically

Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC-1065

The synthesis, physicochemical properties, and biological activities of a series of novel spiro cyclopropyl compounds, modeled on the potent antitumor antibiotic CC-1065 (1), are described. Many of these synthetic analogues are significantly more effectiv

Total Synthesis of U-71,184, A Potent New Antitumor Agent Modeled on CC-1065

The synthesis of U-71,184 (2), a highly potent analog of the novel antitumor antibiotic CC-1065, is described, the penultimate step of which involves the unmasking of a p-hydroxy phenethyl mesylate, which undergoes facile intramolecular elimination to aff