15260-89-6

Upstream product

• 14213-02-6 3-azidoquinoline 
• 64-19-7 acetic acid 
• 99512-72-8 3-amino-4-hydroxyquinoline 
• 899793-06-7 3-(1-hydroxyiminoethyl)-1H-quinolin-4-one 
• 899793-07-8 3-(1-hydroxyiminoethyl)-1H-quinolin-4-one 
• 108-24-7 acetic anhydride 
• 127-09-3 sodium acetate 
• 129377-66-8 3-amino-quinolin-4-ol; hydrochloride 

Relevant academic research and scientific papers

Beckmann rearrangement using indium(III) chloride: Synthesis of substituted oxazoloquinolines from the corresponding ketoximes of 3-acyl-1H-quinolin-4-ones

Nitrilium ion intermediates in the Beckmann rearrangement of 3-acyl-4-quinolinone ketoximes, in the presence of InCl3, were trapped by the β-hydroxy group of the tautomeric form of the ketoxime giving, predominantly, the corresponding oxazoloqu

Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof

Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.