15264-44-5

Usage

Uses

Used in Pharmaceutical Industry:
2,1-Benzisoxazole,6-nitro-(7CI,8CI,9CI) is used as a key intermediate in the synthesis of various pharmaceuticals for its versatile reactivity and functional groups. It contributes to the development of new drugs with potential therapeutic applications.
Used in Organic Chemistry:
In the field of organic chemistry, 2,1-Benzisoxazole,6-nitro-(7CI,8CI,9CI) serves as a valuable building block for the synthesis of complex organic compounds. Its unique structure and functional groups enable the creation of diverse chemical entities with potential applications in various industries.
Used in Agriculture:
2,1-Benzisoxazole,6-nitro-(7CI,8CI,9CI) may find applications in agriculture, particularly in the development of agrochemicals. Its potential use in the synthesis of pesticides, herbicides, or other agricultural chemicals can contribute to more effective and targeted crop protection.
Used in Materials Science:
2,1-Benzisoxazole,6-nitro-(7CI,8CI,9CI)'s unique properties also make it a candidate for use in materials science. 2,1-Benzisoxazole,6-nitro-(7CI,8CI,9CI) could be explored for its potential in creating new materials with specific properties, such as high thermal stability, electrical conductivity, or optical characteristics.
Used in Biological Research:
Given its potential biological activity, 2,1-Benzisoxazole,6-nitro-(7CI,8CI,9CI) may be studied for its pharmacological properties. Researchers could investigate its interactions with biological systems, exploring its potential as a therapeutic agent or its effects on cellular processes.

InChI:InChI=1/C7H4N2O3/c10-9(11)6-2-1-5-4-12-8-7(5)3-6/h1-4H

Upstream product

• 2200-86-4 1-(2,4-dinitrophenyl)propan-2-one 
• 121-14-2 2,4-dinitrotoluene 
• 528-75-6 2,4-dinitrobenzaldehyde 

Downstream Products

• 83516-92-1 6-Phenyl-6H-5a-nitro-5a,6a-dihydro<5,6>cyclopropabenzo<1,2-c>isoxazole 
• 83516-91-0 6-Nitro-7-diphenylmethyl-2,1-benzisoxazole 
• 983-79-9 benzophenone azine 

Relevant academic research and scientific papers

Pd-Catalyzed Dearomatization of Anthranils with Vinylcyclopropanes by [4+3] Cyclization Reaction

Dearomatization of anthranils with vinylcyclopropanes (VCPs) by Pd-catalyzed [4+3] cyclization reaction has been realized. In the presence of a catalytic amount of borane as an activator, bridged cyclic products were obtained in good to excellent yields with excellent stereoselectivities. By introducing a chiral PHOX ligand (L5), asymmetric dearomatization reactions of anthranils with vinylcyclopropanes proceeded with excellent enantioselectivity. Borane plays a key role for the reactivity, likely owing to the formation of a borane–anthranil complex which has been confirmed by NMR experiments.

Catalyst-free cyclization of anthranils and cyclic amines: One-step synthesis of rutaecarpine

An efficient synthesis of a variety of quinazolinone derivatives via a direct cyclization reaction between commercially available anthranils and cyclic amines is described. The developed transformation proceeds with the merits of high step- and atom-efficiency, a broad substrate scope, and good to excellent yields, without additional catalysts, and offers a practical way for the preparation of rutaecarpine and its derivatives with structural diversity.

Thermal Stability Studies on a Homologous Series of Nitroarenes

The thermal stabilities of a number of nitroarenes were examined in solution and in condensed phase.In general, increasing the number of nitro groups decreased thermal stability.Changing the substituent on 1-X-2,4,6-trinitrobenzene from X = H to NH2 to CH3 to OH accelerated decomposition; this effect was attributed to increased ease of intramolecular proton transfer to an ortho nitro group, thus weakening the carbon-nitrogen bond.In solution, the effect of increasing substitution from n = 1 to n = 3 on Xn(NO2)3C6H3-n was uniformly that of decreasing the thermal stability of the species.However, in condensed phase, results suggested that crystal habit may be more important than molecular structure; for X = Br, CH3, and NH2, the more substituted species was the more stable.