983-79-9Relevant academic research and scientific papers
Synthesis of 3-(2-Oxo-2,3-dihydrobenzo[b]furan-3-ylidenehydrazono)-2,3- dihydrobenzo[b]furan-2-one
Pulina,Zalesov,Kataev
, p. 861 - 863 (2007)
Reactions of benzophenone and fluoren-9-one hydrazones with (2-hydroxyphenyl)oxoacetic acid gave [carboxy(2-hydroxyphenyl) methylidenehydrazono](2-hydroxyphenyl)acetic acid which underwent intramolecular cyclization with formation of 3-(2-oxo-2,3-dihydrob
Synthesis of symmetrical and asymmetrical azines from hydrazones and/or ferrocenecarboxaldehyde as potential antimicrobial–antitumor agents
Lasri, Jamal,Aly, Magda M.,Eltayeb, Naser Eltaher,Babgi, Bandar A.
, p. 1 - 8 (2018)
9-Fluorenone azine 2a and benzophenone azine 2b were synthesized, respectively, by treatment of 9-fluorenone hydrazone 1a or benzophenone hydrazone 1b with FeCl3 in chloroform. Ferrocenecarboxaldehyde 3 reacts with 1a or 1b, in ethanol, to furn
Cobalt(II) complex of a diazoalkane radical anion
Bonyhady, Simon J.,Goldberg, Jonathan M.,Wedgwood, Nicole,Dugan, Thomas R.,Eklund, Andrew G.,Brennessel, William W.,Holland, Patrick L.
, p. 5148 - 5150 (2015)
β-Diketiminate cobalt(I) precursors react with diphenyldiazomethane to give a compound that is shown by computational studies to be a diazoalkane radical anion antiferromagnetically coupled to a high-spin cobalt(II) ion. Thermolysis of this complex result
Iron and Cobalt Diazoalkane Complexes Supported by β-Diketiminate Ligands: A Synthetic, Spectroscopic, and Computational Investigation
Bonyhady, Simon J.,Derosha, Daniel E.,Vela, Javier,Vinyard, David J.,Cowley, Ryan E.,Mercado, Brandon Q.,Brennessel, William W.,Holland, Patrick L.
, p. 5959 - 5972 (2018)
Diazoalkanes are interesting redox-active ligands and also precursors to carbene fragments. We describe a systematic study of the binding and electronic structure of diphenyldiazomethane complexes of β-diketiminate supported iron and cobalt, which span a
Preparation and application of 5-bromoquinazoline derivative
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Paragraph 0035-0037, (2021/02/16)
The invention discloses a 5-bromoquinazoline derivative shown in the corresponding formula. A synthesis method of the 5-bromoquinazoline derivative compound (I) comprises the following steps: weighing1.18 g of 5-bromoisatin, 2.5503g of ammonium formate an
Preparation and application of chiral quaternary ammonium salt
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Paragraph 0039-0041, (2021/08/07)
The invention provides preparation of chiral quaternary ammonium salt. The structural formula is as follows: a synthesis method of the chiral quaternary ammonium salt compound (I) comprises the following steps: using 10 mol% zinc chloride as a catalyst, firstly adding 22 mmol of anhydrous ZnCl2, 50 mL of absolute methanol, 2.1639 g of sodium hydroxide and 1.5656 g of D-valinol, refluxing the mixture at high temperature for 60 h, stopping the reaction, dissolving the residue with water, extracting with CH2Cl2 (20 mL * 3), drying the organic phase with anhydrous sodium sulfate, rotating to remove the solvent, and recrystallizing the crude product with dichloromethane and absolute ethyl alcohol to obtain a colorless crystal; the application of the chiral quaternary ammonium salt compound (I) is characterized in that the chiral quaternary ammonium salt compound has good catalytic performance in a nitrile silicification reaction of benzaldehyde and a condensation reaction of benzophenone hydrazone, and the conversion rates respectively reach up to 71% and 99%.
Formation of Osmium Alkylidene, Alkylidyne, and Dinitrogen Complexes from Reactions of OsCl2(PPh3)3with Diazoalkanes
Cui, Mingxu,Jia, Guochen,Sung, Herman H. Y.,Williams, Ian D.
, p. 3833 - 3842 (2021/11/18)
The reactions of OsCl2(PPh3)3 with a series of diazoalkanes were investigated. The reactions with monosubstituted diazoalkanes N2CHR gave the desired osmium alkylidene complexes OsCl2(=CHR)(PPh3)2, the stability of which is dependent on the substituent on the alkylidene carbons. The five-coordinate osmium alkylidene complex OsCl2(=CHCOOMe)(PPh3)2 is thermally stable, whereas the analogous complex OsCl2(=CH-p-tol)(PPh3)2 readily rearranges to its hydrido-alkylidyne form OsHCl2(C-p-tol)(PPh3)2. A substitution reaction of OsCl2(=CHCOOMe)(PPh3)2 with PCy3 produced the hydrido-alkylidyne complex OsHCl2(CCOOMe)(PCy3)2, revealing the effect of the phosphine on the relative stability of OsCl2(=CHCOOMe)(PR3)2 and OsHCl2(CCOOMe)(PR3)2. The reaction of OsCl2(PPh3)3 with the acceptor-acceptor disubstituted diazoalkane dibenzoyl diazomethane, bearing COPh substituents, led to the formation of the metallacyclic complex OsCl2{κ2-N,O-[N2C(COPh)C(Ph)O]}(PPh3)2 due to the chelating effect of dibenzoyl diazomethane. The complex OsCl2(PPh3)3 catalyzed the homocoupling of the diazoalkane N2CPh2 to give the azine Ph2C=N-N=CPh2. The η1-N2 coordinated binuclear complex (Ph3P)2ClOs(μ-Cl)3Os(PPh3)2(N2) was isolated as a minor product, which was considered to be an off-cycle product in the catalytic reaction.
Grignard reagent dictated copper(I) phosphines catalyzed reductive coupling of diazo compounds: The chemistry beyond carbene generation
Kuzhalmozhi Madarasi, Packirisamy,Sivasankar, Chinnappan
, (2021/12/01)
Copper-dppf catalyzed reductive coupling of diazo compounds through terminal nitrogen is reported. However, copper catalysts are known to produce carbene from diazo compounds; the reaction conditions played an important role in the formation of diazine over carbene generation. Several control experiments have been conducted to understand the reaction mechanism and found that the formation of a copper–Mg heterobimetallic complex would be responsible for the observed reactivity pattern. The reaction produced diazine as a reductive coupling product along with biphenyl as a by-product. All the synthesized diazines have been characterized fully by using analytical and spectroscopic techniques.
Application of chiral oxazoline-copper complex
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Page/Page column 8, (2020/01/25)
An application of a bis{2-[4(R)-phenyl-4,5-dihydro]-2-oxazoline}phenol-copper complex with a chemical formula shown in the description is characterized in that the complex has a good catalysis performance when used as a catalyst for a reaction of diphenyl
Preparation and application of chiral zinc complex
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Paragraph 0028-0030, (2020/10/14)
The invention discloses a chiral zinc complex, which is prepared from anhydrous zinc chloride and L-phenylglycinol. Compounds are represented by the following Chemical Formula in the specification. The invention discloses a synthetic method of a chiral zi
