15288-08-1

Usage

Chemical class

Beta-adrenergic agonist

Common use

Bronchodilator for asthma and COPD treatment

Mechanism of action

Relaxes smooth muscles in airways, easing breathing

Anti-inflammatory properties

Potential to reduce airway inflammation

Available forms

Inhalers, tablets, and oral solutions

Precautions

Use with caution and under medical supervision

Potential side effects

Tremors, palpitations, increased heart rate

Upstream product

• 71031-03-3 (R)-phenyl glycidyl ether 
• 109-89-7 diethylamine 
• 108-95-2 phenol 
• 95207-41-3 3-diethylamino-1-phenoxy-2-trimethylsiloxypropane 
• 122-60-1 Phenyl glycidyl ether 
• 106-89-8 epichlorohydrin 

Relevant academic research and scientific papers

Double-Hydrogen-Bonding Catalysis of the Reaction of Phenyl Glycidyl Ether with Diethylamine by 1,8-Biphenylenediol

The reaction of phenyl glycidyl ether with diethylamine in butanone gives 3-(diethylamino)-1-phenoxy-2-propanol.Catalysis by phenol and five of its meta- and para-substituted derivatives gives catalysis constants that obey the Broensted equation well, wit

Light induced activity switch in interfacial hydrogen-bond catalysis with photo sensitive metal oxides

UV light switches on the catalytic activities of several metal oxides in hydrogen bond catalyzed reactions because of the changes in the concentration of the surface hydroxyl groups. The Royal Society of Chemistry 2009.

Highly chemoselective addition of amines to epoxides in water

(Chemical Equation Presented) Aminolysis of a variety of epoxides by aliphatic and aromatic amines in water, in the absence of any catalyst with high yields, is reported. β-Amino alcohols were formed under mild conditions with high selectivity and in excellent yields.

A new and efficient epoxide ring opening via poor nucleophiles: Indole, p-nitroaniline, borane and O-trimethylsilylhydroxylamine in lithium perchlorate

Highly regioselective ring opening of 2,3-dimethyloxirane, 2-epoxyphenylether and allyl(2-epoxymethyl) ether are observed through reactions with poor nucleophiles such as indole, borane, O-trimethylsilylhydroxylamine, p-nitroaniline and sterically hindered tert-butylamine in the presence of 5.0 M lithium perchlorate-Et2O solution. These reactions are fast, convenient, with rather high yields and are carried out at ambient temperatures.

Calcium trifluoromethanesulfonate-catalysed aminolysis of epoxides

Aminolysis of epoxides catalysed by calcium trifluoromethanesulfonate under mild reaction conditions is described. The novel method is very efficient in the synthesis of wide variety of β-amino alcohols with high regio- and stereoselectivity.

Enantioselective parallel synthesis using polymer-supported chiral Co(salen) complexes

(matrix presented) The kinetic resolution of epoxides with phenols catalyzed by a polymer-supported Co(salen) complex is applied to the first enantioselective catalytic synthesis of parallel libraries. The corresponding 1-aryloxy-2-alcohols are obtained i

Opening of oxirane ring with N-nucleophiles under microwave irradiation

Opening of oxirane ring under microwave irradiation with various N-nucleophiles in neutral, basic and acidic media is reported. Remarkable rate enhancements and dramatic reductions of reaction times have been observed with better yields.

Lanthanide(III) trifluoromethanesulfonates as extraordinarily effective new catalysts for the aminolysis of 1,2-epoxides

Lanthanide(III) trifluoromethanesulfonates (triflates), such as Yb(OTf)3, Nd(OTf)3 and Gd(OTf)3, catalyze in a extraordinarily efficient way the aminolysis of 1,2-epoxides, affording the corresponding β-amino alcohols, at

Metal salts as new catalysts for mild and efficient aminolysis of oxiranes

A new, simple, efficient, inexpensive, anti stereoselective, highly regioselective method for aminolysis of 1,2-epoxides, by means of metal salts, is described.