15291-75-5 Usage
Description
Ginkgolide A is a crystalline solid belonging to the family of bioactive terpenes. It is a natural compound derived from the Ginkgo biloba tree and has been widely recognized for its various therapeutic properties.
Uses
Used in Pharmaceutical Industry:
Ginkgolide A is used as a cardiovascular and cerebrovascular disease treatment agent due to its ability to act as a specific platelet activating factor (PAF) antagonist. This property helps in preventing blood clot formation and improving blood flow, which is beneficial for patients suffering from these conditions.
Used in Antimicrobial Applications:
Ginkgolide A is used as an antibacterial agent, demonstrating effectiveness against certain bacterial strains. Its antimicrobial properties make it a potential candidate for the development of new antibiotics or as a supplement to existing treatments.
Used in Platelet-Activating Factor (PAF) Antagonism:
Ginkgolide A is used as a PAF antagonist, which plays a crucial role in various physiological processes, including inflammation and immune response. By blocking PAF, Ginkgolide A can help in reducing inflammation and improving overall health.
Check Digit Verification of cas no
The CAS Registry Mumber 15291-75-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,9 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 15291-75:
(7*1)+(6*5)+(5*2)+(4*9)+(3*1)+(2*7)+(1*5)=105
105 % 10 = 5
So 15291-75-5 is a valid CAS Registry Number.
InChI:InChI=1/C20H24O9/c1-7-12(22)26-10-6-17-9-5-8(16(2,3)4)18(17)11(21)13(23)28-15(18)29-20(17,14(24)27-9)19(7,10)25/h7-11,15,21,25H,5-6H2,1-4H3/t7-,8+,9-,10+,11+,15+,17?,18?,19-,20?/m1/s1
15291-75-5Relevant articles and documents
Chemistry of the ginkgolides. Part 10: Access to 14C-labelled ginkgolide A
Weinges, Klaus,Schick, Hartmut,Irngartinger, Hermann,Oeser, Thomas
, p. 3173 - 3176 (2000)
In four reaction steps, ginkgolide A (1) was synthesized from the enol- acetate 3, which is available in six steps from 1. The key step was the react on of the α-epoxy-acetate 4 with the lithium enolate of methyl propionate to give the compounds 5 and 6. 14C-Labelled ginkgolide A, which is of interest for pharmacological studies, can be synthesized using the 14C-labelled methyl propionate. (C) 2000 Elsevier Science Ltd.